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Catalog Number:
38222
CAS Number:
61413-54-5
Rolipram
Purity:
≥ 98 % (HPLC)
Synonym(s):
4-[3-(Ciclopentiloxi)-4-metoxifenil]-2-pirrolidinona, Número de pieza ZK62711
Documents
$220.33 /50 mg
Tamaño
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Información del producto

Rolipram is a selective phosphodiesterase-4 (PDE4) inhibitor that has garnered significant attention in the fields of pharmacology and neuroscience. This compound is recognized for its potential therapeutic applications, particularly in the treatment of depression, anxiety disorders, and neurodegenerative diseases. By inhibiting the breakdown of cyclic adenosine monophosphate (cAMP), Rolipram enhances intracellular signaling pathways, which can lead to improved mood and cognitive function. Its unique ability to cross the blood-brain barrier makes it particularly valuable for neurological research and drug development.

In addition to its applications in mental health, Rolipram has been studied for its anti-inflammatory properties, showing promise in conditions such as asthma and chronic obstructive pulmonary disease (COPD). Researchers are exploring its potential in enhancing memory and learning, making it a compound of interest in cognitive enhancement studies. With its specific action on PDE4, Rolipram stands out among similar compounds, offering targeted therapeutic benefits with a favorable safety profile. This makes it an essential candidate for researchers and industry professionals focused on innovative treatments for complex disorders.

Número CAS
61413-54-5
Fórmula molecular
C16H21NO3
Peso molecular
275.35
Número MDL
MFCD00270906
Punto de fusión
130 - 134 °C
Condiciones
Conservar a < -20 °C
Información general
Número CAS
61413-54-5
Fórmula molecular
C16H21NO3
Peso molecular
275.35
Número MDL
MFCD00270906
Punto de fusión
130 - 134 °C
Condiciones
Conservar a < -20 °C
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

Rolipram is widely utilized in research focused on:

  • Neuropharmacology: It acts as a selective phosphodiesterase-4 (PDE4) inhibitor, which can enhance cognitive function and has potential applications in treating neurodegenerative diseases like Alzheimer's.
  • Anti-inflammatory therapies: By inhibiting PDE4, Rolipram reduces the production of pro-inflammatory cytokines, making it a candidate for developing treatments for chronic inflammatory conditions such as asthma and rheumatoid arthritis.
  • Psychiatric disorders: Research indicates its efficacy in improving symptoms of depression and anxiety, providing a new avenue for developing antidepressant medications.
  • Cardiovascular health: The compound shows promise in protecting against heart failure by modulating inflammatory responses and improving cardiac function.
  • Drug delivery systems: Rolipram can be incorporated into nanocarriers for targeted drug delivery, enhancing the efficacy of therapeutic agents in treating various diseases.

Citas