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Catalog Number:
38166
CAS Number:
57-66-9
Probenecida
Purity:
≥ 98% (ensayo por titulación, HPLC)
Synonym(s):
Ácido 4-( N,N -dipropilsulfamoil)benzoico, Ácido 4-(di- n -propilaminosulfonil)benzoico
Documents
$79.22 /25G
Tamaño
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Información del producto

Probenecid is a versatile compound primarily recognized for its role as a uricosuric agent in the treatment of gout and hyperuricemia. This sulfonamide derivative enhances the excretion of uric acid by inhibiting its reabsorption in the renal tubules, making it a valuable tool in managing conditions associated with elevated uric acid levels. Beyond its therapeutic applications, Probenecid is also utilized in pharmaceutical formulations to prolong the action of certain antibiotics, such as penicillin, by inhibiting their renal excretion. This dual functionality makes Probenecid an essential compound in both clinical and research settings.

In addition to its medicinal uses, Probenecid's unique properties allow for its application in various biochemical studies, particularly in the exploration of renal transport mechanisms. Researchers appreciate its ability to modulate drug pharmacokinetics, which can lead to enhanced therapeutic outcomes. With its established efficacy and broad applicability, Probenecid continues to be an important compound for healthcare professionals and researchers alike, offering significant benefits in both treatment and scientific exploration.

Número CAS
57-66-9
Fórmula molecular
C13H19NO4S
Peso molecular
285.36
Número MDL
MFCD00038402
Punto de fusión
198-202 °C
Condiciones
Conservar entre 2 y 8 °C.
Información general
Número CAS
57-66-9
Fórmula molecular
C13H19NO4S
Peso molecular
285.36
Número MDL
MFCD00038402
Punto de fusión
198-202 °C
Condiciones
Conservar entre 2 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

Probenecid is widely utilized in research focused on

  • Gout Treatment: Probenecid is primarily used to manage gout by increasing uric acid excretion in the kidneys, helping to lower uric acid levels in the blood and prevent painful flare-ups.
  • Enhancing Antibiotic Efficacy: In clinical settings, it is employed to prolong the action of certain antibiotics, such as penicillin, by inhibiting their renal excretion, thus allowing for lower doses and reduced side effects.
  • Pharmacokinetic Studies: Researchers use probenecid in pharmacokinetic studies to understand drug interactions and metabolism, particularly in assessing how drugs are absorbed, distributed, and eliminated by the body.
  • Research on Renal Function: It serves as a valuable tool in nephrology research, helping scientists investigate renal function and the mechanisms of renal transport processes.
  • Potential Cancer Research: Emerging studies suggest probenecid may have applications in cancer therapy, as it can influence the transport of certain anticancer drugs, potentially enhancing their effectiveness.

Citas