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Catalog Number:
38101
CAS Number:
63675-72-9
Nisoldipina
Purity:
≥ 99,5 % (ensayo, en base seca)
Synonym(s):
Éster metílico de isobutil del ácido 1,4-dihidro-2,6-dimetil-4-(2-nitrofenil)-3,5-piridinadicarboxílico, Metil-1,4-dihidro-2,6-dimetil-4-(2-nitrofenil)-3,5-piridinadicarboxilato de isobutilo
Documents
$130.60 /1G
Tamaño
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Información del producto

Nisoldipine is a potent calcium channel blocker primarily used in the management of hypertension and angina pectoris. This compound works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. Its unique structure, characterized by a 2-nitrophenyl group and multiple methyl substitutions, enhances its efficacy and selectivity, making it a preferred choice for patients who require effective blood pressure control with minimal side effects.

In addition to its cardiovascular applications, Nisoldipine has shown promise in research settings, particularly in studies exploring its effects on various vascular conditions. Its ability to selectively target calcium channels can be beneficial in developing treatments for other diseases where calcium regulation is crucial. Researchers and healthcare professionals appreciate Nisoldipine for its consistent performance and favorable pharmacokinetic profile, which allows for once-daily dosing, improving patient compliance.

Número CAS
63675-72-9
Fórmula molecular
C20H24N2O6
Peso molecular
388.42
Número MDL
MFCD00478055
Punto de fusión
148 - 152 °C
Condiciones
Conservar entre 2 y 8 °C.
Información general
Número CAS
63675-72-9
Fórmula molecular
C20H24N2O6
Peso molecular
388.42
Número MDL
MFCD00478055
Punto de fusión
148 - 152 °C
Condiciones
Conservar entre 2 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

Nisoldipine is widely utilized in research focused on:

  • Cardiovascular Health: This compound is primarily used as an antihypertensive agent, helping to lower blood pressure in patients with hypertension. It relaxes blood vessels, improving blood flow and reducing the risk of heart-related issues.
  • Pharmaceutical Development: Researchers are exploring its potential in developing new medications for cardiovascular diseases. Its unique properties make it a candidate for formulations aimed at improving patient compliance and efficacy.
  • Clinical Trials: Nisoldipine is often involved in clinical studies to assess its effectiveness and safety in various populations, providing valuable data that can influence treatment guidelines.
  • Combination Therapies: It is frequently studied in combination with other antihypertensive drugs to enhance therapeutic outcomes, allowing for lower doses and reduced side effects compared to monotherapy.
  • Research on Drug Delivery Systems: The compound is being investigated for its role in novel drug delivery methods, which can improve the bioavailability and targeted action of cardiovascular medications.

Citas