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Catalog Number:
37690
CAS Number:
96187-53-0
Brequinar
Synonym(s):
Ácido 6-fluoro-2-(2'-fluoro-[1,1'-bifenil]-4-il)-3-metilquinolin-4-carboxílico
Documents
$65.00 /25 mg
Tamaño
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Información del producto

Brequinar is a potent quinoline derivative known for its selective inhibition of dihydroorotate dehydrogenase, making it a valuable compound in the field of immunology and oncology. This compound has garnered attention for its potential applications in the treatment of autoimmune diseases and certain types of cancer, particularly due to its ability to modulate lymphocyte proliferation and function. Researchers have explored its use in combination therapies, enhancing the efficacy of existing treatments while minimizing side effects.

In addition to its therapeutic applications, Brequinar's unique chemical structure allows for targeted drug delivery systems, which can improve bioavailability and reduce systemic toxicity. Its effectiveness in preclinical studies highlights its promise as a lead compound for further development in pharmaceutical formulations. With ongoing research, Brequinar holds significant potential for advancing treatment options in various medical fields, making it an essential compound for researchers and industry professionals focused on innovative therapeutic solutions.

Número CAS
96187-53-0
Fórmula molecular
C23H15F2NO2
Peso molecular
375.37
Número MDL
MFCD00866437
Punto de fusión
317 ?C
Condiciones
Conservar entre 2 y 8 °C.
Información general
Número CAS
96187-53-0
Fórmula molecular
C23H15F2NO2
Peso molecular
375.37
Número MDL
MFCD00866437
Punto de fusión
317 ?C
Condiciones
Conservar entre 2 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
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Aplicaciones

Brequinar is widely utilized in research focused on:

  • Antiviral Research: Brequinar has shown potential as an antiviral agent, particularly in studies targeting viral replication mechanisms. Its unique structure allows it to inhibit specific enzymes, making it valuable in developing treatments for viral infections.
  • Cancer Therapy: This compound is being explored for its ability to inhibit cell proliferation in various cancer types. Researchers are investigating its effectiveness in combination therapies to enhance the efficacy of existing cancer treatments.
  • Immunosuppressive Applications: Brequinar has been studied for its immunosuppressive properties, which can be beneficial in organ transplantation and autoimmune disease management. By modulating immune responses, it helps in reducing the risk of rejection in transplant patients.
  • Biochemical Research: As a tool in biochemical studies, Brequinar is used to investigate metabolic pathways and enzyme activities. Its specific interactions with cellular components make it a useful reagent in laboratory settings.
  • Drug Development: The compound serves as a lead structure in drug discovery programs, allowing researchers to modify its chemical properties to enhance potency and reduce side effects. This adaptability makes it a significant candidate in pharmaceutical development.

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