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Catalog Number:
33604
CAS Number:
1217768-67-6
Fmoc-4-cloro-2-fluoro-D-fenilalanina
Synonym(s):
Fmoc-D-Phe(4-Cl,2-F)-OH, (Ácido R -Fmoc-2-amino-4-cloro-2-fluorofenilpropiónico
Documents
$58.39 /100 mg
Tamaño
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Product Information

Fmoc-4-chloro-2-fluoro-D-phenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective modification of amino acids during solid-phase peptide synthesis (SPPS). Its distinctive structure, characterized by the presence of both a chlorine and a fluorine atom on the aromatic ring, enhances its reactivity and allows for the introduction of diverse functionalities in peptide sequences. Researchers and professionals in the pharmaceutical industry can leverage this compound for the synthesis of bioactive peptides, which are crucial in therapeutic applications, including cancer treatment and antibiotic development.

The incorporation of Fmoc-4-chloro-2-fluoro-D-phenylalanine into peptide chains can improve the stability and efficacy of the resulting compounds, making it an attractive choice for those looking to develop novel therapeutics. Its unique properties also enable the exploration of structure-activity relationships, aiding in the design of more effective drug candidates. With its practical applications in medicinal chemistry and biochemistry, this compound stands out as a key building block for innovative research and development.

Synonyms
Fmoc-D-Phe(4-Cl,2-F)-OH, (Ácido R -Fmoc-2-amino-4-cloro-2-fluorofenilpropiónico
CAS Number
1217768-67-6
Molecular Formula
C24H19ClFNO4
Molecular Weight
439.86
MDL Number
MFCD12198171
PubChem ID
53398088
Conditions
Conservar entre 2 y 8 °C.
General Information
Synonyms
Fmoc-D-Phe(4-Cl,2-F)-OH, (Ácido R -Fmoc-2-amino-4-cloro-2-fluorofenilpropiónico
CAS Number
1217768-67-6
Molecular Formula
C24H19ClFNO4
Molecular Weight
439.86
MDL Number
MFCD12198171
PubChem ID
53398088
Conditions
Conservar entre 2 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-chloro-2-fluoro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as an essential building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its protective Fmoc group allows for selective deprotection, facilitating the assembly of complex peptide sequences.
  • Drug Development: It is used in the design of novel pharmaceuticals, especially in the development of peptide-based drugs. The unique fluorine and chlorine substitutions can enhance the biological activity and stability of drug candidates.
  • Bioconjugation: This chemical is valuable in bioconjugation processes, where it can be linked to other biomolecules, such as antibodies or enzymes, to create targeted therapies or diagnostic tools in the biomedical field.
  • Research in Neuroscience: Its structural properties make it a candidate for studying neurotransmitter interactions, helping researchers understand the mechanisms of action for various neuroactive compounds.
  • Material Science: The compound can be incorporated into polymer matrices, contributing to the development of advanced materials with tailored properties for applications in coatings, sensors, and drug delivery systems.

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