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Catalog Number:
30544
CAS Number:
359780-63-5
N α -Fmoc-N ε -(2-nitrobencenosulfonil)-L-lisina
Purity:
≥ 99 % (HPLC)
Synonym(s):
Nα-Fmoc-Nε-Nosil-L-lisina, Fmoc-L-Lys(Ns)-OH
Documents
$75.50 /250 mg
Tamaño
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Product Information

Modificación postsintética de péptidos mediante N-alquilación quimioselectiva de sus cadenas laterales. L.Monfregola et.al., Org.Lett.,2012, 14(7), 1644-1667; Véase también: Tetr.Lett., 2005, 46, 6637-6640 y Amino Acids, 2011, 41(4), 981-990.

Synonyms
Nα-Fmoc-Nε-Nosil-L-lisina, Fmoc-L-Lys(Ns)-OH
CAS Number
359780-63-5
Purity
≥ 99 % (HPLC)
Molecular Formula
C27H27N3O8S
Molecular Weight
553.6
MDL Number
MFCD22989438
PubChem ID
138109651
Melting Point
56-62 °C
Appearance
Polvo amorfo blanco cristalino o blanquecino
Optical Rotation
[a] D 20 = - 11 ± 2º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Nα-Fmoc-Nε-Nosil-L-lisina, Fmoc-L-Lys(Ns)-OH
CAS Number
359780-63-5
Purity
≥ 99 % (HPLC)
Molecular Formula
C27H27N3O8S
Molecular Weight
553.6
MDL Number
MFCD22989438
PubChem ID
138109651
Melting Point
56-62 °C
Appearance
Polvo amorfo blanco cristalino o blanquecino
Optical Rotation
[a] D 20 = - 11 ± 2º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-Nosyl-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions and the formation of complex structures. Its stability under various conditions makes it a preferred choice for researchers in organic chemistry.
  • Drug Development: In pharmaceutical research, it is used to create novel drug candidates by modifying peptide sequences, which can lead to improved efficacy and reduced side effects in therapeutic applications.
  • Bioconjugation: The compound facilitates the attachment of biomolecules to surfaces or other molecules, enhancing the development of targeted drug delivery systems and diagnostic tools in biotechnology.
  • Protein Engineering: Researchers utilize it in the design of modified proteins, which can exhibit enhanced stability and activity, crucial for applications in enzyme technology and therapeutic proteins.
  • Research in Cancer Therapeutics: Its role in synthesizing peptide-based inhibitors allows for the exploration of new cancer treatments, providing a pathway for developing more effective therapies with fewer side effects.

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