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Catalog Number:
30527
CAS Number:
1016163-79-3
Ácido 2-( R )-Fmoc-amino-3-azidopropiónico
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-D-Ala(N3)-OH, Fmoc-D-Dap(N3)-OH
Documents
$65.40 /100 mg
Tamaño
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Product Information

2-(R)-Fmoc-amino-3-azidopropionic acid is a versatile building block in peptide synthesis, particularly valued for its unique azido functional group, which allows for further modifications through click chemistry. This compound serves as an essential intermediate in the development of peptide-based therapeutics and bioconjugates, making it a crucial tool for researchers in medicinal chemistry and drug development. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group facilitates easy incorporation into peptide chains while ensuring stability during synthesis.

The compound's ability to participate in bioorthogonal reactions expands its utility in labeling and tracking biomolecules, enhancing its relevance in fields such as proteomics and molecular biology. Researchers can leverage its properties to create targeted drug delivery systems or study protein interactions, showcasing its potential in advancing scientific knowledge and therapeutic strategies. With its unique features and practical applications, 2-(R)-Fmoc-amino-3-azidopropionic acid stands out as an indispensable asset for professionals aiming to innovate in peptide chemistry.

Synonyms
Fmoc-D-Ala(N3)-OH, Fmoc-D-Dap(N3)-OH
CAS Number
1016163-79-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C18H16N4O4
Molecular Weight
352.3
MDL Number
MFCD18427301
PubChem ID
71439801
Melting Point
118 - 124 ?C
Appearance
Polvo cristalino blanco
Optical Rotation
[a] D 20 = 9 ± 2 º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-D-Ala(N3)-OH, Fmoc-D-Dap(N3)-OH
CAS Number
1016163-79-3
Purity
≥ 99 % (HPLC)
Molecular Formula
C18H16N4O4
Molecular Weight
352.3
MDL Number
MFCD18427301
PubChem ID
71439801
Melting Point
118 - 124 ?C
Appearance
Polvo cristalino blanco
Optical Rotation
[a] D 20 = 9 ± 2 º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-(R)-Fmoc-amino-3-azidopropionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of azide groups that facilitate further modifications.
  • Click Chemistry: Its azide functionality enables applications in click chemistry, a powerful method for bioconjugation, allowing researchers to create complex biomolecules efficiently and selectively.
  • Drug Development: The compound is used in the development of novel pharmaceuticals, particularly in creating targeted therapies where specific modifications can enhance drug efficacy and reduce side effects.
  • Biomaterials: It finds applications in the design of biomaterials, where the azide group can be utilized for cross-linking and functionalizing surfaces, improving biocompatibility for medical devices.
  • Fluorescent Probes: Researchers utilize this compound in the creation of fluorescent probes for imaging applications, enabling the study of cellular processes with high specificity and sensitivity.

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