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Catalog Number:
30043
CAS Number:
4105-38-8
2',3',5'- tri - O -acetiluridina
Purity:
≥ 98 % (HPLC)
Synonym(s):
Uridina 2',3',5'-triacetato
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Product Information

2',3',5'-tri-O-Acetyluridine is a versatile nucleoside derivative that plays a significant role in biochemical research and pharmaceutical applications. This compound is recognized for its stability and solubility, making it an excellent choice for various laboratory experiments, particularly in the synthesis of oligonucleotides and nucleoside analogs. Its acetyl groups enhance its lipophilicity, facilitating cellular uptake and making it a valuable tool in drug development and delivery systems. Researchers often utilize 2',3',5'-tri-O-Acetyluridine in studies involving RNA synthesis and modification, as well as in the exploration of antiviral and anticancer therapies, where it can serve as a precursor for more complex nucleoside structures.

The unique properties of 2',3',5'-tri-O-Acetyluridine, such as its ability to protect the hydroxyl groups during chemical reactions, provide significant advantages in synthetic pathways. This compound is particularly beneficial in the development of therapeutics targeting viral infections and cancer, where precise modifications of nucleosides can enhance efficacy and reduce side effects. Its application in the synthesis of nucleotide analogs underscores its importance in the field of medicinal chemistry, making it a crucial component for researchers aiming to innovate in drug design and development.

Synonyms
Uridina 2',3',5'-triacetato
CAS Number
4105-38-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C15H18N2O9
Molecular Weight
370.31
MDL Number
MFCD00023795
PubChem ID
254731
Appearance
Polvo cristalino blanco o casi blanco.
Conditions
Conservar a -20 °C
General Information
Synonyms
Uridina 2',3',5'-triacetato
CAS Number
4105-38-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C15H18N2O9
Molecular Weight
370.31
MDL Number
MFCD00023795
PubChem ID
254731
Appearance
Polvo cristalino blanco o casi blanco.
Conditions
Conservar a -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2',3',5'-tri-O-Acetyluridine is widely utilized in research focused on:

  • Nucleic Acid Research: This compound serves as a key building block in the synthesis of modified nucleotides, which are essential for studying RNA structure and function.
  • Drug Development: It plays a significant role in the formulation of antiviral agents, particularly those targeting RNA viruses, enhancing their efficacy and stability.
  • Biotechnology: Used in the production of RNA-based therapeutics, it helps in the development of mRNA vaccines and gene therapies, addressing critical health challenges.
  • Analytical Chemistry: This chemical is employed as a standard in chromatographic techniques, aiding in the accurate analysis of nucleosides and nucleotides in various samples.
  • Pharmaceutical Formulations: Its acetyl groups improve solubility and bioavailability, making it a valuable ingredient in the design of oral drug formulations.

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