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Catalog Number:
30002
CAS Number:
302-95-4
Desoxicolato de sodio
Purity:
≥ 99% (titulación)
Synonym(s):
Sal sódica del ácido 7-desoxicólico, Sal sódica del ácido 5b-colan-24-oico-3a,12a-diol
Documents
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Tamaño
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Product Information

Sodium deoxycholate is a bile salt that plays a crucial role in various biochemical applications, particularly in the fields of biochemistry and pharmaceuticals. This compound is widely recognized for its ability to solubilize lipids and proteins, making it an essential reagent in the preparation of cell membranes and in the extraction of membrane proteins. Its amphiphilic nature allows it to act as a surfactant, which is beneficial in drug formulation and delivery systems, enhancing the bioavailability of poorly soluble compounds.

In research, sodium deoxycholate is often utilized in the isolation and purification of nucleic acids, as well as in the development of liposomes for targeted drug delivery. Its effectiveness in disrupting lipid bilayers makes it a valuable tool in cell lysis protocols, facilitating the study of cellular components. Additionally, sodium deoxycholate is employed in various diagnostic assays and as a stabilizing agent in protein formulations, underscoring its versatility and importance in both laboratory and industrial settings.

Synonyms
Sal sódica del ácido 7-desoxicólico, Sal sódica del ácido 5b-colan-24-oico-3a,12a-diol
CAS Number
302-95-4
Purity
≥ 99% (titulación)
Molecular Formula
C24H39O4Na
Molecular Weight
414.56
MDL Number
MFCD00064139
PubChem ID
3440164
Appearance
Polvo cristalino de color blanco a blanquecino.
Optical Rotation
[a] D 20 = +44 ± 2º (C=2%, H 2 O)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Sal sódica del ácido 7-desoxicólico, Sal sódica del ácido 5b-colan-24-oico-3a,12a-diol
CAS Number
302-95-4
Purity
≥ 99% (titulación)
Molecular Formula
C24H39O4Na
Molecular Weight
414.56
MDL Number
MFCD00064139
PubChem ID
3440164
Appearance
Polvo cristalino de color blanco a blanquecino.
Optical Rotation
[a] D 20 = +44 ± 2º (C=2%, H 2 O)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Sodium deoxycholate is widely utilized in research focused on:

  • Cell Membrane Studies: This compound is often used to solubilize membrane proteins, making it easier for researchers to study their structure and function. Its ability to disrupt lipid bilayers is crucial for understanding cellular processes.
  • Drug Delivery Systems: Sodium deoxycholate serves as an effective emulsifier in pharmaceutical formulations, enhancing the bioavailability of poorly soluble drugs. This is particularly beneficial in the development of oral and injectable medications.
  • Biotechnology Applications: In the production of vaccines and therapeutic proteins, it aids in the purification processes by removing contaminants, thus improving yield and quality.
  • Analytical Chemistry: It is used in various assays and chromatographic techniques, helping to improve the resolution and sensitivity of detection methods for biomolecules.
  • Cosmetic Formulations: Sodium deoxycholate is incorporated into skincare products for its emulsifying properties, allowing for better texture and stability in creams and lotions.

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