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Catalog Number:
27073
CAS Number:
70-00-8
5-trifluorotimidina
Purity:
≥ 99,5 % (HPLC)
Synonym(s):
Trifluridina, Desoxirribosido de trifluorotimina
Documents
$62.29 /100 mg
Tamaño
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Product Information

5-Trifluorothymidine is a fluorinated nucleoside analog that has garnered significant attention in the fields of medicinal chemistry and virology. This compound is particularly notable for its antiviral properties, making it a valuable candidate in the development of therapies against viral infections, including herpes simplex virus and other DNA viruses. Its unique trifluoromethyl group enhances its metabolic stability and bioavailability, which can lead to improved therapeutic outcomes compared to non-fluorinated analogs. Researchers have utilized 5-Trifluorothymidine in various studies to explore its potential as a treatment option, demonstrating its efficacy in inhibiting viral replication.

In addition to its antiviral applications, 5-Trifluorothymidine is also being investigated for its role in cancer therapy, particularly in targeting rapidly dividing cells. Its structural similarity to thymidine allows it to be incorporated into DNA, which can disrupt the replication process in cancerous cells. This dual functionality makes 5-Trifluorothymidine a versatile compound for both antiviral and anticancer research, offering promising avenues for the development of new therapeutic strategies.

Synonyms
Trifluridina, Desoxirribosido de trifluorotimina
CAS Number
70-00-8
Purity
≥ 99,5 % (HPLC)
Molecular Formula
C10H11F3N2O5
Molecular Weight
296.2
MDL Number
MFCD00006534
PubChem ID
253083
Melting Point
186-189 ?C
Appearance
Polvo cristalino blanco
Optical Rotation
[a] D 20 = + 49 ± 2º (C=0,3% en H 2 O)
Conditions
Conservar a ≤ -4 °C
General Information
Synonyms
Trifluridina, Desoxirribosido de trifluorotimina
CAS Number
70-00-8
Purity
≥ 99,5 % (HPLC)
Molecular Formula
C10H11F3N2O5
Molecular Weight
296.2
MDL Number
MFCD00006534
PubChem ID
253083
Melting Point
186-189 ?C
Appearance
Polvo cristalino blanco
Optical Rotation
[a] D 20 = + 49 ± 2º (C=0,3% en H 2 O)
Conditions
Conservar a ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Trifluorothymidine is widely utilized in research focused on:

  • Antiviral Research: This compound is primarily used in the development of antiviral therapies, particularly against herpes simplex virus (HSV) and other viral infections, providing a crucial tool for researchers in virology.
  • Pharmaceutical Development: It serves as an important intermediate in the synthesis of nucleoside analogs, which are essential in creating new antiviral drugs, enhancing the arsenal of treatments available to healthcare professionals.
  • Diagnostic Applications: 5-Trifluorothymidine can be used in imaging techniques for tracking viral infections, allowing for better diagnostic capabilities in clinical settings.
  • Research in Cancer Therapy: Its properties make it a candidate for research into targeted cancer therapies, particularly in studies involving thymidine metabolism and its effects on tumor cells.
  • Biochemical Studies: The compound is utilized in various biochemical assays to study DNA synthesis and repair mechanisms, providing insights that are valuable for both academic and industrial research.

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