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Catalog Number:
24750
CAS Number:
41906-86-9
Nitrocefina
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$160.00 /5 mg
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Product Information

Nitrocefin is a highly regarded chromogenic substrate widely utilized in microbiology and biochemistry for the detection of beta-lactamases, enzymes produced by certain bacteria that confer antibiotic resistance. This compound is particularly valuable in clinical laboratories for its ability to provide rapid and reliable results in identifying bacterial resistance to beta-lactam antibiotics, such as penicillins and cephalosporins. Nitrocefin undergoes a distinct color change upon hydrolysis by beta-lactamases, making it an essential tool for researchers and healthcare professionals aiming to combat antibiotic resistance effectively.

In addition to its diagnostic applications, Nitrocefin is also employed in various research settings to study enzyme kinetics and mechanisms. Its unique structural properties allow for specific interactions with beta-lactamases, providing insights into enzyme activity and resistance patterns. This compound stands out due to its ease of use and the speed at which it delivers results, making it a preferred choice for laboratories focused on antibiotic susceptibility testing and microbial resistance research.

CAS Number
41906-86-9
Molecular Formula
C21H16N4O8S2
Molecular Weight
516.51
MDL Number
MFCD00864896
PubChem ID
74926725
Conditions
Conservar entre 0 y 8 °C.
General Information
CAS Number
41906-86-9
Molecular Formula
C21H16N4O8S2
Molecular Weight
516.51
MDL Number
MFCD00864896
PubChem ID
74926725
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nitrocefin is widely utilized in research focused on:

  • Antibiotic Resistance Studies: Nitrocefin serves as a chromogenic substrate for detecting β-lactamase enzymes, which are responsible for antibiotic resistance. This application is crucial for researchers studying the mechanisms of resistance in bacteria.
  • Microbial Identification: In microbiology, Nitrocefin is used to identify various bacterial species by testing their ability to hydrolyze the compound, providing a quick and effective method for pathogen detection.
  • Pharmaceutical Development: The compound is employed in drug formulation and testing, particularly in the development of new antibiotics, helping researchers evaluate the efficacy of potential drug candidates against resistant strains.
  • Environmental Monitoring: Nitrocefin can be used in environmental science to assess the presence of β-lactamase-producing bacteria in soil and water samples, aiding in the understanding of antibiotic contamination in ecosystems.
  • Biotechnology Applications: In biotechnology, Nitrocefin is utilized in assays to monitor enzyme activity, particularly in the development of biosensors that detect bacterial contamination in food and clinical samples.

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