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Catalog Number:
24446
CAS Number:
24589-78-4
2,2,2-Trifluoro- N -metil- N -(trimetilsilil)acetamida
Purity:
≥ 98% (GC)
Synonym(s):
N -Trimetilsilil- N -metil trifluoroacetamida
Hazmat
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Product Information

2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide is a versatile chemical compound widely utilized in the field of organic synthesis and analytical chemistry. This compound is particularly valued for its role as a derivatizing agent, enhancing the detection and analysis of various functional groups in complex mixtures. Its unique trifluoromethyl group contributes to its strong electron-withdrawing properties, making it an excellent choice for improving the volatility and stability of analytes during gas chromatography. Researchers often leverage this compound in the preparation of derivatives for mass spectrometry, facilitating the identification of biomolecules and pharmaceuticals.

Additionally, 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide is recognized for its ability to form stable silyl derivatives, which are crucial in the characterization of alcohols, amines, and carboxylic acids. Its compatibility with a wide range of solvents and its ease of use in laboratory settings make it an essential tool for chemists aiming to streamline their workflows and enhance analytical precision. This compound stands out in comparison to similar reagents due to its superior stability and efficiency in derivatization processes.

Synonyms
N -Trimetilsilil- N -metil trifluoroacetamida
CAS Number
24589-78-4
Purity
≥ 98% (GC)
Molecular Formula
C6H12F3NOSi
Molecular Weight
199.25
MDL Number
MFCD00000411
PubChem ID
32510
Density
1,075 g/mL a 25 °C
Appearance
Líquido transparente, incoloro a amarillento.
Boiling Point
130 - 132 ?C
Refractive Index
número 20/D 1,38
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
N -Trimetilsilil- N -metil trifluoroacetamida
CAS Number
24589-78-4
Purity
≥ 98% (GC)
Molecular Formula
C6H12F3NOSi
Molecular Weight
199.25
MDL Number
MFCD00000411
PubChem ID
32510
Density
1,075 g/mL a 25 °C
Appearance
Líquido transparente, incoloro a amarillento.
Boiling Point
130 - 132 ?C
Refractive Index
número 20/D 1,38
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile reagent in organic chemistry, facilitating the synthesis of various fluorinated compounds, which are important in pharmaceuticals and agrochemicals.
  • Mass Spectrometry: It acts as a derivatizing agent, enhancing the volatility and stability of polar compounds for analysis, making it invaluable in analytical chemistry.
  • Fluorination Reactions: The trifluoromethyl group allows for selective fluorination, which is crucial in developing new materials and fine chemicals, particularly in the electronics and materials science industries.
  • Biological Studies: Its unique properties help in studying the interactions of fluorinated compounds with biological systems, aiding drug discovery and development.
  • Environmental Applications: The compound can be used in the synthesis of environmentally friendly solvents and materials, aligning with the growing demand for sustainable chemistry practices.

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