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Catalog Number:
21640
CAS Number:
703-95-7, 207291-81-1
Ácido 5-fluoroorótico
Purity:
≥ 98 % (HPLC)
Synonym(s):
5' de altura, Ácido 5-fluorouracilo-4-carboxílico
Documents
$51.18 /1G
Tamaño
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Product Information

5-Fluoroorotic acid is a fluorinated derivative of orotic acid, recognized for its significant role in various biochemical applications. This compound is particularly valued in the field of cancer research, where it serves as a potent inhibitor of pyrimidine metabolism. Its unique structure allows it to interfere with nucleic acid synthesis, making it a valuable tool for studying cellular processes and the effects of fluorinated compounds on biological systems. Researchers utilize 5-Fluoroorotic acid in the development of targeted therapies, as it can selectively affect rapidly dividing cells, a hallmark of many cancers.

In addition to its applications in cancer research, 5-Fluoroorotic acid is also explored for its potential in metabolic studies and as a precursor in the synthesis of other fluorinated compounds. Its ability to enhance the understanding of metabolic pathways makes it an essential reagent in pharmaceutical development and biochemical research. The compound's stability and reactivity further contribute to its utility in various laboratory settings, providing researchers with a reliable resource for advancing their studies.

Synonyms
5' de altura, Ácido 5-fluorouracilo-4-carboxílico
CAS Number
703-95-7, 207291-81-1
Purity
≥ 98 % (HPLC)
Molecular Formula
C5H3FN2O4
Molecular Weight
174.09
MDL Number
MFCD00042526
PubChem ID
69711
Appearance
Polvo cristalino de color blanquecino a amarillo.
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
5' de altura, Ácido 5-fluorouracilo-4-carboxílico
CAS Number
703-95-7, 207291-81-1
Purity
≥ 98 % (HPLC)
Molecular Formula
C5H3FN2O4
Molecular Weight
174.09
MDL Number
MFCD00042526
PubChem ID
69711
Appearance
Polvo cristalino de color blanquecino a amarillo.
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Fluoroorotic acid is widely utilized in research focused on:

  • Anticancer Research: It serves as a potent inhibitor of orotate phosphoribosyltransferase, making it valuable in developing cancer therapies that target nucleotide synthesis.
  • Pharmaceutical Development: This compound is used in synthesizing various pharmaceuticals, particularly in the creation of fluorinated nucleotides, which are crucial for certain antiviral and anticancer drugs.
  • Metabolic Studies: Researchers employ it to study metabolic pathways involving pyrimidine nucleotides, helping to understand diseases related to nucleotide metabolism.
  • Genetic Research: It is used in genetic experiments to create selective pressure in microbial cultures, aiding in the study of gene function and regulation.
  • Biotechnology Applications: The compound is utilized in biotechnology for developing genetically modified organisms (GMOs) that can efficiently produce nucleotides, enhancing agricultural productivity.

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