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Catalog Number:
20981
CAS Number:
6160-80-1
4-Metilumbeliferil-β-D(-)-glucurónido dihidrato
Purity:
≥ 99 % (HPLC)
Synonym(s):
7-Hidroxi-4-metilcumarina-β-D-glucurónido
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$29.34 /1G
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Product Information

4-Methylumbelliferyl-b-D(-)-glucuronide dihydrate is a valuable compound widely utilized in biochemical research and diagnostics. This substrate is particularly significant for its role in enzyme assays, specifically for detecting the activity of β-glucuronidase. Its fluorescent properties make it an excellent choice for applications in fluorescence microscopy and flow cytometry, enabling researchers to visualize enzymatic activity with high sensitivity. The compound's ability to produce a fluorescent signal upon hydrolysis allows for real-time monitoring of enzyme kinetics, making it an essential tool in pharmacokinetics and toxicology studies.

In addition to its applications in research, 4-Methylumbelliferyl-b-D(-)-glucuronide dihydrate is also used in clinical laboratories for the assessment of liver function and the detection of certain diseases. Its unique features, such as high solubility and stability, enhance its usability in various experimental conditions. This compound stands out among similar substrates due to its specific reactivity and the clarity of the fluorescent signal it generates, providing researchers with reliable and reproducible results.

Synonyms
7-Hidroxi-4-metilcumarina-β-D-glucurónido
CAS Number
6160-80-1
Purity
≥ 99 % (HPLC)
Molecular Formula
C16H16O9 · 2H2O
Molecular Weight
388.32
MDL Number
MFCD00151678
PubChem ID
3683393
Appearance
Polvo cristalino blanco
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
7-Hidroxi-4-metilcumarina-β-D-glucurónido
CAS Number
6160-80-1
Purity
≥ 99 % (HPLC)
Molecular Formula
C16H16O9 · 2H2O
Molecular Weight
388.32
MDL Number
MFCD00151678
PubChem ID
3683393
Appearance
Polvo cristalino blanco
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Methylumbelliferyl-b-D(-)-glucuronide dihydrate is widely utilized in research focused on:

  • Enzyme Activity Assays: This compound serves as a substrate for glucuronidase enzymes, allowing researchers to measure enzyme activity in various biological samples.
  • Drug Metabolism Studies: It is used to investigate the metabolism of drugs in the liver, providing insights into how substances are processed and eliminated from the body.
  • Fluorescent Probes: The compound exhibits fluorescence upon hydrolysis, making it a valuable tool for visualizing enzyme activity in live cells and tissues.
  • Biochemical Research: It aids in the study of glycosylation processes, which are crucial for understanding cell signaling and the development of certain diseases.
  • Pharmaceutical Development: This chemical is instrumental in the development of new drugs by helping to assess the pharmacokinetics and bioavailability of therapeutic compounds.

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