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Catalog Number:
16739
CAS Number:
1175838-03-5
Fmoc-α-metil-L-4-fluorofenilalanina
Purity:
≥ 99,5 % (HPLC quiral)
Synonym(s):
Fmoc-α-Me-L-Phe(4-F)-OH, Ácido Fmoc-( S )-2-amino-2-metil-3-(4-fluorofenil)propanoico
Documents
$90.00 /100 mg
Tamaño
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Product Information

Fmoc-a-methyl-L-4-Fluorophenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethyloxycarbonyl) protecting group, which facilitates the selective protection of the amino group during the synthesis of peptides. Its structure, characterized by the presence of a fluorophenyl group, enhances the compound's hydrophobicity and can influence the biological activity of the resulting peptides. Researchers and industry professionals leverage Fmoc-a-methyl-L-4-Fluorophenylalanine for the development of novel therapeutic agents, particularly in the fields of medicinal chemistry and biochemistry.

The compound's ability to improve the stability and solubility of peptides makes it an essential tool in the design of peptide-based drugs. Its application extends to the synthesis of peptide libraries for high-throughput screening, allowing for the rapid identification of potential drug candidates. Additionally, the incorporation of fluorinated amino acids like Fmoc-a-methyl-L-4-Fluorophenylalanine can enhance the pharmacokinetic properties of peptides, making them more effective in therapeutic applications. This compound stands out for its versatility and effectiveness in advancing peptide synthesis and drug discovery.

Synonyms
Fmoc-α-Me-L-Phe(4-F)-OH, Ácido Fmoc-( S )-2-amino-2-metil-3-(4-fluorofenil)propanoico
CAS Number
1175838-03-5
Purity
≥ 99,5 % (HPLC quiral)
Molecular Formula
C 25 H 22 FNO 4
Molecular Weight
419.44
MDL Number
MFCD08061624
PubChem ID
53398475
Appearance
Sólido de color blanco a blanquecino
Optical Rotation
[a] D 20 = -12 ± 2 ° (C=1 en MeOH)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-α-Me-L-Phe(4-F)-OH, Ácido Fmoc-( S )-2-amino-2-metil-3-(4-fluorofenil)propanoico
CAS Number
1175838-03-5
Purity
≥ 99,5 % (HPLC quiral)
Molecular Formula
C 25 H 22 FNO 4
Molecular Weight
419.44
MDL Number
MFCD08061624
PubChem ID
53398475
Appearance
Sólido de color blanco a blanquecino
Optical Rotation
[a] D 20 = -12 ± 2 ° (C=1 en MeOH)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-a-methyl-L-4-Fluorophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its unique fluorinated structure enhances the biological activity of peptides, making it valuable in the pharmaceutical industry for developing new drugs with improved efficacy and selectivity.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it can be attached to biomolecules for targeted drug delivery systems, enhancing the therapeutic potential of various treatments.
  • Research in Cancer Therapeutics: Researchers utilize this compound to explore its effects on cancer cell lines, aiding in the development of targeted therapies that can specifically attack cancer cells while minimizing damage to healthy tissues.
  • Fluorinated Amino Acid Studies: It plays a significant role in studies focused on the properties of fluorinated amino acids, contributing to the understanding of their behavior in biological systems and their potential applications in medicinal chemistry.

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