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Catalog Number:
11336
CAS Number:
200871-84-7
Boc-D-His(3-Me)-OH
Purity:
≥ 99 % (TLC)
Synonym(s):
Boc-D-His(π-Me)-OH, Boc- N -π-metil-D-histidina
Documents
$95.00 /25 mg
Tamaño
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Información del producto

Boc-D-His(3-Me)-OH is a valuable amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a protected histidine residue, making it an essential building block for the development of bioactive peptides and proteins. Its unique structure, characterized by the presence of a tert-butoxycarbonyl (Boc) protecting group, allows for selective reactions, enhancing the efficiency of synthetic pathways. Researchers appreciate its stability and compatibility with various coupling reagents, which facilitates the formation of complex peptide sequences.

In the pharmaceutical industry, Boc-D-His(3-Me)-OH is particularly relevant for the design of therapeutic peptides that target specific biological pathways. Its application extends to the development of drug candidates with improved efficacy and reduced side effects. Additionally, this compound is instrumental in the study of histidine's role in enzyme catalysis and protein interactions, providing insights that can lead to innovative therapeutic strategies. With its robust properties and versatility, Boc-D-His(3-Me)-OH stands out as a crucial tool for researchers and industry professionals alike.

Número CAS
200871-84-7
Fórmula molecular
C12H19N3O4
Peso molecular
269.3
Número MDL
MFCD00237545
Punto de fusión
176 - 184 °C
Rotación óptica
[a] D 24 = -24,6 ± 2 º (C=1% en MeOH)
Condiciones
Conservar entre 0 y 8 °C.
Información general
Número CAS
200871-84-7
Fórmula molecular
C12H19N3O4
Peso molecular
269.3
Número MDL
MFCD00237545
Punto de fusión
176 - 184 °C
Rotación óptica
[a] D 24 = -24,6 ± 2 º (C=1% en MeOH)
Condiciones
Conservar entre 0 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

Boc-D-His(3-Me)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of therapeutic proteins and biologics. Its protective Boc group allows for selective reactions, enhancing the efficiency of peptide assembly.
  • Drug Development: In medicinal chemistry, it plays a crucial role in designing new drug candidates, especially those targeting histidine residues in proteins, which are vital for enzyme activity and receptor binding.
  • Bioconjugation: The compound is used in bioconjugation processes, facilitating the attachment of biomolecules to drugs or imaging agents, which can improve drug delivery and efficacy in targeted therapies.
  • Protein Engineering: Researchers leverage Boc-D-His(3-Me)-OH in protein engineering to modify histidine residues, enhancing protein stability and functionality, which is essential in biopharmaceutical applications.
  • Analytical Chemistry: It is utilized in analytical methods for the detection and quantification of histidine-containing compounds, aiding in quality control and research in food and pharmaceutical industries.

Citas