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Catalog Number:
07393
CAS Number:
238742-88-6
Fmoc-D-Phe(4- CF3 )-OH
Purity:
≥ 98% (HPLC quiral)
Synonym(s):
Fmoc-4-trifluorometil-D-fenilalanina
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$120.58 /1G
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Product Information

Fmoc-D-Phe(4-CF3)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. The presence of the trifluoromethyl group enhances its lipophilicity and stability, making it particularly valuable in the design of bioactive peptides and pharmaceuticals. Researchers appreciate its utility in solid-phase peptide synthesis (SPPS), where it facilitates the assembly of complex peptide structures with high purity and yield.

In addition to its role in peptide synthesis, Fmoc-D-Phe(4-CF3)-OH is also explored in medicinal chemistry for the development of novel therapeutics targeting various diseases. Its unique properties allow for the fine-tuning of peptide properties, such as solubility and bioavailability, which are crucial for effective drug formulation. This compound stands out among similar derivatives due to its enhanced stability and functional versatility, making it an essential tool for researchers and industry professionals focused on peptide-based drug discovery and development.

Synonyms
Fmoc-4-trifluorometil-D-fenilalanina
CAS Number
238742-88-6
Purity
≥ 98% (HPLC quiral)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD00797582
PubChem ID
4445976
Appearance
Polvo blanco
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-4-trifluorometil-D-fenilalanina
CAS Number
238742-88-6
Purity
≥ 98% (HPLC quiral)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD00797582
PubChem ID
4445976
Appearance
Polvo blanco
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-Phe(4-CF3)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Its unique trifluoromethyl group enhances the pharmacological properties of peptides, making it valuable in the design of more effective therapeutic agents.
  • Bioconjugation: The compound can be used to create bioconjugates, linking peptides to other biomolecules, which is crucial in developing targeted drug delivery systems.
  • Research in Neuroscience: It is employed in studies involving neuropeptides, helping researchers understand their role in neurological functions and disorders.
  • Analytical Chemistry: The compound aids in the development of analytical methods for peptide characterization, ensuring the quality and efficacy of peptide-based drugs.

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