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Catalog Number:
05728
CAS Number:
71989-25-8
Éster 4-nitrofenílico de Fmoc-L-leucina
Purity:
≥ 99 % (TLC)
Synonym(s):
Fmoc-L-Leu-ONp, ( S) -Éster 4-nitrofenílico del ácido Fmoc-2-amino-4-metil-pentanoico
Documents
$29.34 /1G
Tamaño
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Información del producto

Fmoc-L-leucine 4-nitrophenyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound serves as a protective group for the amino acid leucine, enabling chemists to selectively modify or couple it during the synthesis of complex peptides. Its unique structure, featuring the Fmoc (9-fluorenylmethoxycarbonyl) group, provides excellent stability under basic conditions while allowing for easy removal under mild acidic conditions, making it an ideal choice for researchers looking to streamline their synthesis processes.

In addition to its role in peptide synthesis, Fmoc-L-leucine 4-nitrophenyl ester is also employed in the development of pharmaceutical compounds, particularly in the creation of biologically active peptides. Its ability to enhance solubility and stability of peptide chains can lead to improved bioavailability and efficacy of therapeutic agents. Researchers in medicinal chemistry and biochemistry will find this compound invaluable for its efficiency and effectiveness in producing high-quality peptides for various applications, including drug discovery and development.

Número CAS
71989-25-8
Fórmula molecular
C27H26N2O6
Peso molecular
474.51
Número MDL
MFCD00038536
Punto de fusión
114-120 ?C
Rotación óptica
[a] D 24 = -48 ± 2º (C=1% en dimetilformamida y 1% de ácido acético)
Condiciones
Conservar entre 0 y 8 °C.
Información general
Número CAS
71989-25-8
Fórmula molecular
C27H26N2O6
Peso molecular
474.51
Número MDL
MFCD00038536
Punto de fusión
114-120 ?C
Rotación óptica
[a] D 24 = -48 ± 2º (C=1% en dimetilformamida y 1% de ácido acético)
Condiciones
Conservar entre 0 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
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Aplicaciones

Fmoc-L-leucine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.
  • Drug Development: It is used in the development of peptide-based drugs, providing a means to modify peptide structures for enhanced therapeutic effects.
  • Bioconjugation: The compound facilitates the attachment of peptides to other biomolecules, which is crucial in creating targeted drug delivery systems.
  • Research in Protein Engineering: It aids in the study of protein interactions and modifications, helping scientists understand protein functions and develop novel proteins.
  • Analytical Chemistry: Fmoc-L-leucine 4-nitrophenyl ester is employed in various analytical techniques, including chromatography, to analyze peptide compositions and purities.

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