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Catalog Number:
05474
CAS Number:
145881-13-6
N α - Boc- N ω,ω' -bis-ZD-arginina
Purity:
≥ 98 % (HPLC)
Synonym(s):
Boc-D-Arg(Z) 2 -OH
Documents
$93.14 /250 mg
Tamaño
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Información del producto

Na-Boc-Nw,w'-bis-Z-D-arginine is a highly specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its ability to enhance the stability and bioavailability of peptides, making it an essential tool for researchers in pharmaceutical and biochemical fields. Its unique structure, featuring two phenylmethoxycarbonyl groups, allows for effective protection of the amino groups during synthesis, facilitating the creation of complex peptide sequences with improved efficacy.

In practical applications, Na-Boc-Nw,w'-bis-Z-D-arginine is often utilized in the development of therapeutic peptides, especially those targeting specific receptors or pathways in the body. Its ability to provide steric hindrance and protect sensitive functional groups makes it ideal for use in solid-phase peptide synthesis. Researchers have successfully employed this compound in the design of peptides for cancer therapy and other critical medical applications, highlighting its versatility and importance in advancing drug discovery.

Número CAS
145881-13-6
Fórmula molecular
C27H34N4O8
Peso molecular
542.6
Número MDL
MFCD00236825
Punto de fusión
133 - 139 ?C
Rotación óptica
[a] 20 D = 4 ± 2 ° (C = 1 en DMF)
Condiciones
Conservar a ≤ -4 °C
Información general
Número CAS
145881-13-6
Fórmula molecular
C27H34N4O8
Peso molecular
542.6
Número MDL
MFCD00236825
Punto de fusión
133 - 139 ?C
Rotación óptica
[a] 20 D = 4 ± 2 ° (C = 1 en DMF)
Condiciones
Conservar a ≤ -4 °C
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

Na-Boc-Nw,w'-bis-Z-D-arginine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial for creating complex peptides used in drug development.
  • Drug Development: It plays a significant role in the design of peptide-based therapeutics, particularly in targeting specific biological pathways, which can lead to more effective treatments with fewer side effects.
  • Bioconjugation: The compound is used in bioconjugation techniques, where it helps in attaching drugs to antibodies or other biomolecules, enhancing the specificity and efficacy of targeted therapies.
  • Research in Immunology: It is valuable in studies related to immune response modulation, as it can be incorporated into molecules that interact with immune cells, aiding in the development of vaccines and immunotherapies.
  • Analytical Chemistry: This chemical can be utilized in analytical methods to study protein interactions and stability, providing insights that are essential for both academic research and industrial applications.

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