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Catalog Number:
04153
CAS Number:
205526-29-0
Fmoc-4-yodo-D-fenilalanina
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-D-Phe(4-I)-OH, Fmoc -p -yodo-D-Phe-OH
Documents
$36.65 /1G
Tamaño
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Product Information

Fmoc-4-iodo-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. The presence of the iodine atom on the phenyl ring enhances its utility in various labeling and imaging applications, making it a valuable tool for researchers in medicinal chemistry and biochemistry.

With its unique properties, Fmoc-4-iodo-D-phenylalanine is particularly advantageous for the synthesis of peptides with specific functionalities, including those used in targeted drug delivery systems and therapeutic agents. Its ability to facilitate the introduction of iodine into peptide structures opens up possibilities for developing radiolabeled compounds for diagnostic imaging. Researchers can leverage this compound to create innovative solutions in drug design and development, ensuring high specificity and efficacy in their applications.

Synonyms
Fmoc-D-Phe(4-I)-OH, Fmoc -p -yodo-D-Phe-OH
CAS Number
205526-29-0
Purity
≥ 99 % (HPLC)
Molecular Formula
C 24 H 20 INOX 4
Molecular Weight
513.4
MDL Number
MFCD00672557
PubChem ID
4456487
Melting Point
173 - 177 ?C
Appearance
Sólido de color blanco a blanquecino
Optical Rotation
[a] 25 D = 21 ± 1 ° (C = 1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-D-Phe(4-I)-OH, Fmoc -p -yodo-D-Phe-OH
CAS Number
205526-29-0
Purity
≥ 99 % (HPLC)
Molecular Formula
C 24 H 20 INOX 4
Molecular Weight
513.4
MDL Number
MFCD00672557
PubChem ID
4456487
Melting Point
173 - 177 ?C
Appearance
Sólido de color blanco a blanquecino
Optical Rotation
[a] 25 D = 21 ± 1 ° (C = 1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-iodo-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of iodine into peptide sequences, which can be useful for labeling and tracking in biological studies.
  • Drug Development: Its unique structure makes it valuable in the development of novel pharmaceuticals, especially in designing compounds that target specific receptors or enzymes, enhancing the efficacy of drug candidates.
  • Bioconjugation: The iodine atom can facilitate bioconjugation reactions, enabling researchers to attach biomolecules to surfaces or other molecules, which is crucial in the development of targeted therapies and diagnostics.
  • Research in Cancer Therapy: Due to its ability to selectively target cancer cells, it is being explored in the design of anticancer agents, potentially leading to more effective treatments with fewer side effects.
  • Fluorescent Labeling: The compound can be used in fluorescent labeling techniques, providing a means for visualizing and tracking proteins in live cells, which is essential for understanding cellular processes.

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