Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
04143
CAS Number:
198545-72-1
Fmoc-3-fluoro-D-fenilalanina
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-D-Fe(3-F)-OH, Fmoc -m -fluoro-D-Phe-OH
Documents
$35.00 /1G
Tamaño
Request Bulk Quote
Product Information

Fmoc-3-fluoro-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. The presence of a fluorine atom enhances its bioactivity and stability, making it a valuable building block in the design of novel therapeutics. Researchers and industry professionals appreciate its role in the development of peptide-based drugs, particularly in the fields of oncology and neurology, where precise modifications can lead to improved efficacy and reduced side effects.

This compound is particularly advantageous for solid-phase peptide synthesis (SPPS), allowing for efficient coupling reactions and facilitating the introduction of fluorinated residues into peptides. Its unique properties enable the creation of peptides with enhanced pharmacological profiles, which can be crucial in the development of targeted therapies. Fmoc-3-fluoro-D-phenylalanine stands out among similar compounds due to its ability to improve the solubility and stability of peptides, making it an essential tool for researchers aiming to innovate in drug design and development.

Synonyms
Fmoc-D-Fe(3-F)-OH, Fmoc -m -fluoro-D-Phe-OH
CAS Number
198545-72-1
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 20 FNO 4
Molecular Weight
405.4
MDL Number
MFCD00672554
PubChem ID
3625607
Melting Point
150 - 160 ?C
Appearance
Polvo blanco
Optical Rotation
[a] D 20 = +43,5 ± 3,5º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-D-Fe(3-F)-OH, Fmoc -m -fluoro-D-Phe-OH
CAS Number
198545-72-1
Purity
≥ 98 % (HPLC)
Molecular Formula
C 24 H 20 FNO 4
Molecular Weight
405.4
MDL Number
MFCD00672554
PubChem ID
3625607
Melting Point
150 - 160 ?C
Appearance
Polvo blanco
Optical Rotation
[a] D 20 = +43,5 ± 3,5º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-fluoro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the efficiency and yield of desired peptide chains.
  • Drug Development: It is used in the development of novel pharmaceutical compounds, especially in designing drugs that target specific receptors, benefiting from its unique fluorinated structure which can improve binding affinity.
  • Bioconjugation: The chemical is valuable in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in creating targeted therapies and diagnostics.
  • Fluorescent Probes: Its properties make it suitable for creating fluorescent probes in biochemical assays, aiding in the visualization of cellular processes and enhancing the sensitivity of detection methods.
  • Research in Neuroscience: The compound is explored in neuroscience research for its potential role in studying neurotransmitter systems, contributing to the understanding of various neurological disorders.

Citas