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Catalog Number:
04138
CAS Number:
205526-26-7
Fmoc-2-fluoro-L-fenilalanina
Purity:
≥ 99,5 % (HPLC quiral)
Synonym(s):
Fmoc-L-Fe(2-F)-OH, Fmoc- o -fluoro-L-Phe-OH, Fmoc-Phe(2-F)-OH
Documents
$36.65 /1G
Tamaño
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Información del producto

Fmoc-2-fluoro-L-phenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a unique fluorine atom, which enhances its bioactivity and selectivity in various applications. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains, making it an essential building block for researchers focused on developing novel therapeutics and biologically active peptides. The presence of the fluorine atom can improve the pharmacokinetic properties of peptides, potentially leading to more effective drug candidates.

In addition to its role in peptide synthesis, Fmoc-2-fluoro-L-phenylalanine is also employed in the development of targeted therapies and diagnostic agents. Its unique properties make it suitable for applications in drug discovery, particularly in the design of inhibitors and modulators for various biological targets. Researchers value this compound for its ability to enhance the efficacy and specificity of peptide-based drugs, making it a crucial tool in the pharmaceutical and biotechnology industries.

Número CAS
205526-26-7
Fórmula molecular
C 24 H 20 FNO 4
Peso molecular
405.4
Número MDL
MFCD00672552
Punto de fusión
120 - 124 °C
Rotación óptica
[a] D 20 = -45 ± 2 ° (C = 1 en DMF)
Condiciones
Conservar entre 0 y 8 °C.
Información general
Número CAS
205526-26-7
Fórmula molecular
C 24 H 20 FNO 4
Peso molecular
405.4
Número MDL
MFCD00672552
Punto de fusión
120 - 124 °C
Rotación óptica
[a] D 20 = -45 ± 2 ° (C = 1 en DMF)
Condiciones
Conservar entre 0 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

Fmoc-2-fluoro-L-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of fluorinated amino acids which can enhance the properties of the resulting peptides.
  • Drug Development: Its unique structure makes it valuable in the design of novel pharmaceuticals, especially in targeting specific receptors or enzymes, which can lead to more effective treatments with fewer side effects.
  • Bioconjugation: The presence of the fluoro group allows for selective labeling and conjugation in biochemistry, facilitating the development of targeted therapies and diagnostic tools in medical research.
  • Research in Protein Engineering: This compound is used to study the effects of fluorinated amino acids on protein folding and stability, providing insights into protein design and function.
  • Analytical Chemistry: It serves as a useful standard in analytical methods for quantifying amino acids and peptides, improving accuracy in research and quality control in pharmaceutical manufacturing.

Citas