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Catalog Number:
03711
CAS Number:
133367-34-7
N α - Fmoc- N im -metiltritil-L-histidina
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-L-His(Mtt)-OH
Documents
$29.34 /1G
Tamaño
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Información del producto

Na-Fmoc-Nim-methyltrityl-L-histidine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which is essential for the selective protection of the amino group during the synthesis of complex peptides. Its unique structure, which includes a methyltrityl group, enhances its stability and solubility, making it an ideal choice for researchers looking to streamline their synthesis processes.

In the pharmaceutical industry, Na-Fmoc-Nim-methyltrityl-L-histidine is particularly valuable for the development of peptide-based therapeutics, including those targeting specific receptors or pathways in various diseases. Its application extends to the creation of bioconjugates and drug delivery systems, where precise control over peptide structure is crucial. Researchers appreciate its ability to facilitate the synthesis of high-purity peptides, ultimately leading to more effective and targeted therapeutic options.

Número CAS
133367-34-7
Fórmula molecular
C41H35N3O4
Peso molecular
633.75
Número MDL
MFCD00153358
Punto de fusión
135-145 °C
Rotación óptica
[α] D 22 = +86 ± 5º (C=5 en CHCl3)
Condiciones
Conservar entre 0 y 8 °C.
Información general
Número CAS
133367-34-7
Fórmula molecular
C41H35N3O4
Peso molecular
633.75
Número MDL
MFCD00153358
Punto de fusión
135-145 °C
Rotación óptica
[α] D 22 = +86 ± 5º (C=5 en CHCl3)
Condiciones
Conservar entre 0 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
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Aplicaciones

Na-Fmoc-Nim-methyltrityl-L-histidine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides that are essential in drug development.
  • Drug Development: Its ability to protect functional groups during chemical reactions makes it valuable in pharmaceutical research, where precise modifications of amino acids are necessary for developing new therapeutic agents.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of peptides to other biomolecules, which is crucial for creating targeted drug delivery systems in cancer therapy.
  • Research in Protein Engineering: Researchers utilize this chemical to modify histidine residues in proteins, enhancing their stability and activity, which is significant in enzyme engineering and biocatalysis.
  • Diagnostic Applications: Its role in the synthesis of peptide-based probes aids in the development of diagnostic tools, improving the detection of diseases through targeted imaging techniques.

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