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Catalog Number:
01236
CAS Number:
320-67-2
5-azacitidina
Purity:
≥ 98 % (HPLC)
Synonym(s):
4-Amino-1-(bD-ribofuranosil)-1,3,5-triazin-2(1H)-ona
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Product Information

5-Azacytidine is a potent nucleoside analog that plays a crucial role in epigenetic research and therapeutic applications. This compound is primarily recognized for its ability to inhibit DNA methylation, making it a valuable tool in the study of gene expression and cellular differentiation. Researchers utilize 5-Azacytidine in cancer research, particularly in the development of treatments for hematological malignancies, as it can reactivate silenced tumor suppressor genes. Its unique structure allows it to integrate into RNA and DNA, leading to altered gene expression profiles, which is essential for understanding various biological processes and disease mechanisms.

In addition to its applications in oncology, 5-Azacytidine is also being explored for its potential in regenerative medicine and stem cell research. By modulating epigenetic marks, it can influence stem cell differentiation and promote tissue regeneration. This compound stands out among similar agents due to its dual action on both DNA and RNA, providing researchers with a versatile tool for manipulating gene expression. With its growing relevance in therapeutic strategies and research, 5-Azacytidine continues to be a compound of interest for professionals in the fields of molecular biology and pharmacology.

Synonyms
4-Amino-1-(bD-ribofuranosil)-1,3,5-triazin-2(1H)-ona
CAS Number
320-67-2
Purity
≥ 98 % (HPLC)
Molecular Formula
C8H12N4O5
Molecular Weight
244.21
MDL Number
MFCD00006539
PubChem ID
1805
Melting Point
228-230 °C (descenso)
Appearance
Polvo cristalino blanco o casi blanco.
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
4-Amino-1-(bD-ribofuranosil)-1,3,5-triazin-2(1H)-ona
CAS Number
320-67-2
Purity
≥ 98 % (HPLC)
Molecular Formula
C8H12N4O5
Molecular Weight
244.21
MDL Number
MFCD00006539
PubChem ID
1805
Melting Point
228-230 °C (descenso)
Appearance
Polvo cristalino blanco o casi blanco.
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Azacytidine is widely utilized in research focused on:

  • Cancer Treatment: This compound is primarily used in oncology to treat certain types of cancer, particularly myelodysplastic syndromes and acute myeloid leukemia, by reactivating silenced genes and promoting normal cell differentiation.
  • Epigenetics Research: It serves as a crucial tool for studying epigenetic modifications, allowing researchers to understand how DNA methylation affects gene expression and cellular behavior.
  • Stem Cell Biology: 5-Azacytidine is applied in stem cell research to induce pluripotency in somatic cells, providing insights into regenerative medicine and potential therapies for degenerative diseases.
  • Drug Development: The compound is used in the development of new therapeutic agents, particularly in the field of epigenetic drugs, offering a novel approach to treating various diseases by targeting gene regulation.
  • Gene Therapy: It is utilized in gene therapy applications to enhance the expression of therapeutic genes, making it a valuable asset in developing innovative treatments for genetic disorders.

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