Descubra el nuevo Chem-Impex: donde la innovación comienza con un vínculo.

Catalog Number:
00713
CAS Number:
109425-51-6
N α -Fmoc- N im -tritil-L-histidina
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-L-His(Trt)-OH
Documents
$20.20 /5G
Tamaño
Request Bulk Quote
Información del producto

Na-Fmoc-Nim-trityl-L-histidine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis of complex peptides. Its trityl group enhances stability and solubility, making it an excellent choice for researchers focused on synthesizing histidine-containing peptides. The unique structure of Na-Fmoc-Nim-trityl-L-histidine not only facilitates the formation of peptide bonds but also improves the overall yield and purity of the final product.

In the pharmaceutical industry, this compound is particularly valuable for developing therapeutic peptides that target specific biological pathways. Its application extends to the synthesis of peptide-based drugs, where the incorporation of histidine can enhance bioactivity and stability. Researchers in biochemistry and medicinal chemistry will find Na-Fmoc-Nim-trityl-L-histidine indispensable for advancing their projects, thanks to its reliable performance and compatibility with various coupling reagents.

Número CAS
109425-51-6
Fórmula molecular
C40H33N3O4
Peso molecular
619.7
Número MDL
MFCD00043332
Rotación óptica
[a] D 20 = 86 ± 8 º (C=5 en CHCl 3 )
Condiciones
Conservar entre 0 y 8 °C.
Información general
Número CAS
109425-51-6
Fórmula molecular
C40H33N3O4
Peso molecular
619.7
Número MDL
MFCD00043332
Rotación óptica
[a] D 20 = 86 ± 8 º (C=5 en CHCl 3 )
Condiciones
Conservar entre 0 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
-
Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

Na-Fmoc-Nim-trityl-L-histidine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides with specific sequences.
  • Drug Development: It plays a significant role in pharmaceutical research, particularly in the development of peptide-based drugs, due to its ability to enhance stability and bioavailability of therapeutic peptides.
  • Bioconjugation: The compound is used in bioconjugation techniques, where it helps to attach biomolecules to surfaces or other molecules, facilitating the development of targeted drug delivery systems.
  • Research in Cancer Therapy: Its applications extend to cancer research, where it is utilized in the design of peptide-based inhibitors that can selectively target cancer cells, improving treatment efficacy.
  • Protein Engineering: This chemical is valuable in protein engineering, aiding researchers in modifying proteins to enhance their function or stability, which is crucial for various biotechnological applications.

Citas