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Catalog Number:
00228
CAS Number:
71989-16-7
N α -Fmoc-L-asparagina
Purity:
≥ 99,5 % (HPLC quiral)
Synonym(s):
Fmoc-L-Asn-OH, Ácido 4-amida Fmoc-( S )-2-aminosuccínico
Documents
$19.73 /5G
Tamaño
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Información del producto

Na-Fmoc-L-asparagine is a versatile amino acid derivative widely utilized in peptide synthesis and biochemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of the amine group during the synthesis of peptides. Its unique structure allows for easy removal of the Fmoc group under mild conditions, making it an ideal choice for researchers looking to streamline their synthesis processes. Na-Fmoc-L-asparagine is particularly valuable in the development of pharmaceuticals, where precise amino acid sequences are crucial for the efficacy of peptide-based drugs.

In addition to its applications in drug development, Na-Fmoc-L-asparagine is also used in the production of peptide libraries for high-throughput screening in drug discovery. Its stability and compatibility with various coupling reagents enhance its utility in solid-phase peptide synthesis (SPPS), allowing for the efficient assembly of complex peptides. Researchers and industry professionals can benefit from its reliable performance and ease of use, making Na-Fmoc-L-asparagine a preferred choice in both academic and industrial settings.

Número CAS
71989-16-7
Fórmula molecular
C19H18N2O5
Peso molecular
354.4
Número MDL
MFCD00037132
Punto de fusión
175 - 195 °C
Rotación óptica
[a] D 20 = -13 ± 3 º (C=1 en DMF)
Condiciones
Conservar entre 0 y 8 °C.
Información general
Número CAS
71989-16-7
Fórmula molecular
C19H18N2O5
Peso molecular
354.4
Número MDL
MFCD00037132
Punto de fusión
175 - 195 °C
Rotación óptica
[a] D 20 = -13 ± 3 º (C=1 en DMF)
Condiciones
Conservar entre 0 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
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Aplicaciones

Na-Fmoc-L-asparagine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the incorporation of asparagine residues. Its protective Fmoc group facilitates efficient coupling reactions.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs, particularly in areas targeting neurological disorders, where asparagine plays a crucial role in neurotransmission.
  • Bioconjugation: Na-Fmoc-L-asparagine is employed in bioconjugation techniques, linking peptides to various biomolecules, enhancing drug delivery systems and improving therapeutic efficacy.
  • Protein Engineering: This compound aids in the design of modified proteins with specific functionalities, which can be crucial for developing novel enzymes or therapeutic proteins.
  • Analytical Chemistry: It is used in analytical applications, such as mass spectrometry, to study peptide fragmentation patterns, helping researchers understand peptide behavior and stability.

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