3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate, commonly known as CHAPS, is a zwitterionic detergent widely utilized in biochemical and molecular biology applications. This compound is particularly effective for solubilizing membrane proteins and stabilizing protein complexes, making it an essential tool in protein purification and analysis. Its unique properties allow for the maintenance of protein functionality while minimizing denaturation, which is crucial for researchers working with sensitive biomolecules. CHAPS is also employed in various applications such as gel electrophoresis, where it aids in the separation of proteins based on size and charge, and in the preparation of samples for mass spectrometry.

In addition to its role in protein research, CHAPS has shown potential in pharmaceutical formulations, particularly in enhancing drug solubility and bioavailability. Its ability to form micelles makes it an excellent candidate for drug delivery systems, providing a pathway for improved therapeutic efficacy. Researchers and industry professionals appreciate CHAPS for its versatility and effectiveness, making it a valuable addition to any laboratory focused on protein studies or drug formulation.