Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
00182
CAS Number:
6066-82-6
N-Hydroxysuccinimide
Purity:
≥ 99% (Assay)
Synonym(s):
NHS, HOSu
Documents
$18.53 /25G
Pack Size Availability Price
Request Bulk Quote
Product Information

N-Hydroxysuccinimide is a versatile compound widely utilized in biochemistry and organic synthesis. This white crystalline solid is recognized for its role as a coupling agent in peptide synthesis, facilitating the formation of amide bonds between carboxylic acids and amines. Its ability to enhance the efficiency of reactions makes it invaluable in the development of pharmaceuticals and bioconjugates. Additionally, N-Hydroxysuccinimide is employed in various applications, including the modification of biomolecules, such as proteins and nucleic acids, which is crucial for research in drug development and diagnostics.

The compound's unique properties, such as its stability and solubility in polar solvents, allow for seamless integration into diverse experimental protocols. Researchers appreciate its effectiveness in improving yields and purities in synthetic processes. Furthermore, N-Hydroxysuccinimide is often used in the preparation of activated esters, which are essential for the conjugation of biomolecules in targeted drug delivery systems. Its broad applicability and efficiency make it a preferred choice for professionals in the pharmaceutical and biotechnology industries.

Synonyms
NHS, HOSu
CAS Number
6066-82-6
Purity
≥ 99% (Assay)
Molecular Formula
C4H5NO3
Molecular Weight
115.1
MDL Number
MFCD00005516
PubChem ID
80170
Melting Point
93 - 100 °C
Appearance
White to yellow crystalline powder
Conditions
Store at RT
General Information
Synonyms
NHS, HOSu
CAS Number
6066-82-6
Purity
≥ 99% (Assay)
Molecular Formula
C4H5NO3
Molecular Weight
115.1
MDL Number
MFCD00005516
PubChem ID
80170
Melting Point
93 - 100 °C
Appearance
White to yellow crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-Hydroxysuccinimide is widely utilized in research focused on:

  • Bioconjugation: It serves as a key reagent for attaching biomolecules, such as proteins or peptides, to surfaces or other molecules, enhancing the development of targeted drug delivery systems.
  • Protein Modification: This compound is commonly used to modify proteins for various applications, including the creation of stable protein conjugates that are essential in vaccine development and diagnostics.
  • Fluorescent Labeling: Researchers use N-Hydroxysuccinimide to create fluorescently labeled compounds, which are crucial for imaging and tracking biological processes in live cells.
  • Polymer Chemistry: It plays a significant role in the synthesis of functionalized polymers, which can be used in drug delivery, tissue engineering, and other advanced materials.
  • Diagnostics: The compound is integral in developing assays and diagnostic kits, particularly in the detection of biomarkers, providing reliable results in clinical settings.

Citations