Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
12881
CAS Number:
148893-10-1
O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
Purity:
≥ 99.5% (HPLC)
Synonym(s):
HATU
Hazmat
Documents
$18.53 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is a versatile reagent widely utilized in organic synthesis and biochemistry. This compound serves as an effective coupling agent, particularly in peptide synthesis and the formation of amide bonds, making it invaluable for researchers in pharmaceutical development and bioconjugation applications. Its unique structure enhances reactivity and solubility, allowing for efficient coupling reactions under mild conditions, which is crucial for maintaining the integrity of sensitive biomolecules.

In addition to its role in peptide synthesis, this compound is also employed in the development of advanced materials and in the modification of surfaces for various applications. Its ability to facilitate the formation of stable linkages makes it a preferred choice for creating complex molecular architectures in drug design and nanotechnology. Researchers and industry professionals benefit from its high efficiency and reliability, which streamline processes and improve yields in synthetic pathways.

Synonyms
HATU
CAS Number
148893-10-1
Purity
≥ 99.5% (HPLC)
Molecular Formula
C10H15F6N6OP
Molecular Weight
380.23
MDL Number
MFCD00274639
PubChem ID
6409673
Melting Point
183 - 191 ?C (dec.)
Appearance
White crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
HATU
CAS Number
148893-10-1
Purity
≥ 99.5% (HPLC)
Molecular Formula
C10H15F6N6OP
Molecular Weight
380.23
MDL Number
MFCD00274639
PubChem ID
6409673
Melting Point
183 - 191 ?C (dec.)
Appearance
White crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a highly effective coupling agent in bioconjugation reactions, allowing researchers to attach biomolecules like proteins and antibodies to surfaces or other molecules, enhancing the functionality of diagnostic and therapeutic agents.
  • Peptide Synthesis: It is commonly used in solid-phase peptide synthesis, providing a reliable method for creating complex peptides with high purity and yield, which is crucial in drug development and research.
  • Fluorescent Labeling: The chemical is employed in the labeling of biomolecules with fluorescent tags, facilitating the study of cellular processes and interactions in live cells, which is essential for biomedical research.
  • Pharmaceutical Development: This compound plays a significant role in the synthesis of pharmaceutical intermediates, streamlining the production of active pharmaceutical ingredients (APIs) and improving the efficiency of drug formulation processes.
  • Material Science: It is utilized in the development of advanced materials, including polymers and coatings, which benefit from enhanced chemical stability and performance, making it valuable in industries like electronics and automotive.

Citations