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Catalog Number:
00618
CAS Number:
68-41-7
D-Cycloserine
Grade:
USP
Synonym(s):
D-4-Amino-3-isoxazolidinone, (R)-4-Amino-3-isoxazolidinone
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Product Information

D-Cycloserine is a versatile compound recognized for its significant role in pharmaceutical applications, particularly in the treatment of tuberculosis and certain psychiatric disorders. This antibiotic, derived from the bacterium *Streptomyces griseus*, exhibits unique properties that make it effective in inhibiting bacterial cell wall synthesis, thereby enhancing therapeutic outcomes in resistant strains of tuberculosis. Additionally, D-Cycloserine has garnered attention in the field of psychiatry, where it is being explored for its potential to augment cognitive behavioral therapy in anxiety disorders and post-traumatic stress disorder (PTSD), showcasing its dual functionality.

Researchers and industry professionals appreciate D-Cycloserine for its ability to cross the blood-brain barrier, which is crucial for its applications in neurology and psychiatry. Its unique mechanism of action not only aids in combating infections but also offers promising avenues for enhancing mental health treatments. With ongoing studies highlighting its efficacy and safety, D-Cycloserine stands out as a compound with significant potential in both infectious disease management and mental health therapies.

Synonyms
D-4-Amino-3-isoxazolidinone, (R)-4-Amino-3-isoxazolidinone
CAS Number
68-41-7
Grade
USP
Molecular Formula
C3H6N2O2
Molecular Weight
102.1
MDL Number
MFCD00005353
PubChem ID
401
Melting Point
147 °C (dec.)
Appearance
White to pale yellow crystalline powder
Optical Rotation
[a]D20 = 108 - 114 º
Conditions
Store at ≤ -4 °C
Potency
≥ 900 µg/mg
General Information
Synonyms
D-4-Amino-3-isoxazolidinone, (R)-4-Amino-3-isoxazolidinone
CAS Number
68-41-7
Grade
USP
Molecular Formula
C3H6N2O2
Molecular Weight
102.1
MDL Number
MFCD00005353
PubChem ID
401
Melting Point
147 °C (dec.)
Appearance
White to pale yellow crystalline powder
Optical Rotation
[a]D20 = 108 - 114 º
Conditions
Store at ≤ -4 °C
Potency
≥ 900 µg/mg
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

D-Cycloserine is widely utilized in research focused on

  • Antibiotic Development: It serves as a second-line treatment for tuberculosis, particularly in cases resistant to first-line antibiotics, enhancing treatment options for patients.
  • Neurological Research: D-Cycloserine is studied for its potential in enhancing learning and memory, making it valuable in cognitive neuroscience and psychiatric research.
  • Psychiatric Disorders: It is being explored as an adjunct therapy for anxiety disorders, including social anxiety and post-traumatic stress disorder (PTSD), offering new avenues for mental health treatment.
  • Drug Development: The compound is used in the development of novel drugs targeting bacterial infections, contributing to the fight against antibiotic resistance.
  • Research on Glutamate Modulation: D-Cycloserine acts as a partial agonist at NMDA receptors, making it a key compound in studies aimed at understanding and treating various neurological conditions.

Citations