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Catalog Number:
37595
CAS Number:
2627-69-2
5-Aminoimidazole-4-carboxamide 1-ß-D-ribofuranoside
Purity:
≥ 98% (HPLC)
Synonym(s):
5-Amino-1-(ß-D-ribofuranosyl)-1H-imidazole-4-carboxamide, AICAR
Documents
$106.96 /50MG
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Product Information

5-Aminoimidazole-4-carboxamide 1-ß-D-ribofuranoside is a vital compound in the field of biochemistry, particularly known for its role as a precursor in the synthesis of nucleotides and nucleic acids. This compound, often referred to as AICAR, is recognized for its potential applications in research related to metabolic pathways and cellular energy regulation. Its unique structure allows it to mimic the effects of adenosine monophosphate (AMP), making it a valuable tool in studies focused on energy metabolism and cellular signaling. Researchers have utilized AICAR in various studies, including those investigating its effects on muscle metabolism and its potential therapeutic applications in conditions such as diabetes and cardiovascular diseases.

The compound's ability to enhance the uptake of glucose and improve insulin sensitivity positions it as a promising candidate for further exploration in metabolic disorders. Additionally, its role in activating AMP-activated protein kinase (AMPK) has garnered interest in the context of exercise physiology and weight management. With its multifaceted applications, 5-Aminoimidazole-4-carboxamide 1-ß-D-ribofuranoside stands out as a significant compound for researchers and industry professionals aiming to explore innovative solutions in health and metabolic research.

Synonyms
5-Amino-1-(ß-D-ribofuranosyl)-1H-imidazole-4-carboxamide, AICAR
CAS Number
2627-69-2
Purity
≥ 98% (HPLC)
Molecular Formula
C9H14N4O5
Molecular Weight
258.23
MDL Number
MFCD00869751
PubChem ID
266934
Melting Point
212 ?C
Appearance
White to light yellow to light red powder to crystal
Optical Rotation
[a]20D = -61 to -66 ° (C=1 in H2O)
Conditions
Store at < 0 °C
General Information
Synonyms
5-Amino-1-(ß-D-ribofuranosyl)-1H-imidazole-4-carboxamide, AICAR
CAS Number
2627-69-2
Purity
≥ 98% (HPLC)
Molecular Formula
C9H14N4O5
Molecular Weight
258.23
MDL Number
MFCD00869751
PubChem ID
266934
Melting Point
212 ?C
Appearance
White to light yellow to light red powder to crystal
Optical Rotation
[a]20D = -61 to -66 ° (C=1 in H2O)
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Aminoimidazole-4-carboxamide 1-ß-D-ribofuranoside is widely utilized in research focused on:

  • Biochemical Research: This compound plays a crucial role in studying cellular metabolism and signaling pathways, particularly in the context of nucleotide synthesis and energy metabolism.
  • Pharmaceutical Development: It is explored for its potential in developing new therapeutic agents, especially in cancer treatment, due to its ability to influence cellular proliferation and apoptosis.
  • Genetic Studies: Researchers use this compound to investigate gene expression and regulation, particularly in studies related to metabolic disorders and genetic diseases.
  • Antioxidant Applications: It has been studied for its antioxidant properties, which can be beneficial in formulating supplements aimed at reducing oxidative stress in various health conditions.
  • Food Industry: The compound is being researched for its potential use as a natural preservative or functional ingredient, enhancing the nutritional profile of food products.

Citations