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Catalog Number:
37535
CAS Number:
21286-54-4
1S-(+)-10-Camphorsulfonyl chloride
Purity:
≥ 97% (GC)(T)
Synonym(s):
(+)-Camphor-10-sulfonyl chloride
Hazmat
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Product Information

(1S)-(+)-10-Camphorsulfonyl chloride is a versatile reagent widely utilized in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. This compound is recognized for its ability to act as a sulfonylating agent, facilitating the introduction of sulfonyl groups into various organic molecules. Its unique structure, derived from camphor, enhances its reactivity and selectivity, making it an invaluable tool for chemists aiming to create complex molecular architectures.

Researchers and industry professionals appreciate (1S)-(+)-10-Camphorsulfonyl chloride for its effectiveness in asymmetric synthesis, where it can help produce chiral sulfonamides with high enantiomeric purity. This property is particularly beneficial in the pharmaceutical industry, where the chirality of compounds can significantly influence their biological activity. Additionally, its application extends to the synthesis of advanced materials and fine chemicals, showcasing its broad utility in both academic and industrial settings.

Synonyms
(+)-Camphor-10-sulfonyl chloride
CAS Number
21286-54-4
Purity
≥ 97% (GC)(T)
Molecular Formula
C10H15ClO3S
Molecular Weight
250.74
MDL Number
MFCD00064156
PubChem ID
265799
Melting Point
65 - 69 °C
Appearance
White to Almost white powder to crystal
Optical Rotation
[α]20D = 31 - 34 ° (C=1, CHCl3)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(+)-Camphor-10-sulfonyl chloride
CAS Number
21286-54-4
Purity
≥ 97% (GC)(T)
Molecular Formula
C10H15ClO3S
Molecular Weight
250.74
MDL Number
MFCD00064156
PubChem ID
265799
Melting Point
65 - 69 °C
Appearance
White to Almost white powder to crystal
Optical Rotation
[α]20D = 31 - 34 ° (C=1, CHCl3)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(1S)-(+)-10-Camphorsulfonyl chloride is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile reagent in organic chemistry, particularly for the synthesis of sulfonamides and sulfonylureas, which are important in pharmaceuticals.
  • Chiral Auxiliary: It acts as a chiral auxiliary in asymmetric synthesis, helping researchers create compounds with specific stereochemistry, which is crucial in drug development.
  • Proteomics: In proteomics, it is used for labeling amino acids, aiding in the study of protein interactions and functions, which is essential for understanding biological processes.
  • Pharmaceutical Development: This chemical is employed in the development of various therapeutic agents, enhancing the efficacy and selectivity of drug candidates.
  • Material Science: It finds applications in the production of advanced materials, including polymers and coatings, due to its reactivity and ability to modify surface properties.

Citations