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Catalog Number:
42194
CAS Number:
1716-12-7
Sodium 4-phenylbutyrate
Purity:
≥ 98% (NMR)
Synonym(s):
4-Phenylbutyric acid sodium salt, 4-PBA
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$119.48 /1G
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Product Information

Sodium 4-phenylbutyrate is a versatile compound recognized for its potential in various applications, particularly in the fields of pharmaceuticals and biochemistry. This sodium salt of 4-phenylbutyric acid has garnered attention for its role as a histone deacetylase (HDAC) inhibitor, making it a valuable tool in cancer research and treatment. Its ability to modulate gene expression presents opportunities for therapeutic interventions in neurodegenerative diseases and metabolic disorders.

In addition to its pharmaceutical applications, Sodium 4-phenylbutyrate is also utilized in cell culture systems to enhance cell viability and promote differentiation. Researchers appreciate its effectiveness in improving the stability of proteins and cellular functions, which can lead to advancements in drug development and regenerative medicine. With its unique properties, Sodium 4-phenylbutyrate stands out as a compound that not only supports scientific research but also holds promise for future therapeutic innovations.

Synonyms
4-Phenylbutyric acid sodium salt, 4-PBA
CAS Number
1716-12-7
Purity
≥ 98% (NMR)
Molecular Formula
C10H11NaO2
Molecular Weight
186.19
MDL Number
MFCD00800247
PubChem ID
5258
Melting Point
220 - 230 ?C
Appearance
White to off-white powder
Conditions
Store at RT
General Information
Synonyms
4-Phenylbutyric acid sodium salt, 4-PBA
CAS Number
1716-12-7
Purity
≥ 98% (NMR)
Molecular Formula
C10H11NaO2
Molecular Weight
186.19
MDL Number
MFCD00800247
PubChem ID
5258
Melting Point
220 - 230 ?C
Appearance
White to off-white powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Sodium 4-phenylbutyrate is widely utilized in research focused on:

  • Neuroprotection: This compound has shown promise in protecting neurons from damage, making it valuable in studies related to neurodegenerative diseases like Huntington's and Alzheimer's.
  • Gene Therapy: It serves as a histone deacetylase inhibitor, which can enhance the effectiveness of gene therapy techniques by promoting gene expression, particularly in cancer research.
  • Metabolic Disorders: Sodium 4-phenylbutyrate is used in the treatment of urea cycle disorders, helping to reduce ammonia levels in patients, thus improving metabolic health.
  • Pharmaceutical Development: Its unique properties make it a candidate for drug formulation, especially in creating therapies that require enhanced bioavailability and stability.
  • Cell Culture Applications: This compound is often added to cell culture media to promote cell growth and differentiation, particularly in stem cell research and regenerative medicine.

Citations