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Catalog Number:
38826
CAS Number:
133073-73-1
Methotrexate hydrate
Grade:
suitable for cell culture
Purity:
≥ 98% (HPLC)
Synonym(s):
4-Amino-10-methylfolic acid hydrate, L-Amethopterin hydrate
Hazmat
Documents
$247.77 /100MG
Pack Size Availability Price
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Product Information

Methotrexate hydrate is a potent antimetabolite and antifolate agent widely utilized in the treatment of various cancers and autoimmune diseases. This compound functions by inhibiting dihydrofolate reductase, thereby disrupting DNA synthesis and cellular replication. Its applications extend beyond oncology, as it is also employed in the management of conditions such as rheumatoid arthritis and psoriasis, showcasing its versatility in therapeutic settings. Researchers and healthcare professionals value Methotrexate hydrate for its efficacy in combination therapies, enhancing the effectiveness of other treatments while minimizing side effects.

In addition to its established medical uses, Methotrexate hydrate is a subject of ongoing research, exploring its potential in novel therapeutic strategies and drug formulations. Its unique properties, including solubility and stability, make it an ideal candidate for pharmaceutical development. With a strong track record in clinical applications, Methotrexate hydrate continues to be a critical component in the arsenal against malignancies and chronic inflammatory diseases, offering significant benefits to patients and healthcare providers alike.

Synonyms
4-Amino-10-methylfolic acid hydrate, L-Amethopterin hydrate
CAS Number
133073-73-1
Purity
≥ 98% (HPLC)
Grade
suitable for cell culture
Molecular Formula
C20H22N8O5·xH2O
Molecular Weight
454.44
MDL Number
MFCD00150847
PubChem ID
24207740
Appearance
Yellow to orange powder
Conditions
Store at < -10 °C
General Information
Synonyms
4-Amino-10-methylfolic acid hydrate, L-Amethopterin hydrate
CAS Number
133073-73-1
Purity
≥ 98% (HPLC)
Grade
suitable for cell culture
Molecular Formula
C20H22N8O5·xH2O
Molecular Weight
454.44
MDL Number
MFCD00150847
PubChem ID
24207740
Appearance
Yellow to orange powder
Conditions
Store at < -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Methotrexate hydrate is widely utilized in research focused on:

  • Cancer Treatment: This compound is a cornerstone in chemotherapy, particularly for treating various types of cancers such as leukemia and lymphoma. Its ability to inhibit cell growth makes it effective in targeting rapidly dividing cancer cells.
  • Autoimmune Disorders: Methotrexate is commonly prescribed for conditions like rheumatoid arthritis and psoriasis. It helps reduce inflammation and suppress the immune system, providing relief to patients.
  • Research in Biochemistry: In laboratory settings, it is used to study metabolic pathways and enzyme activity. Researchers utilize it to understand folate metabolism and its implications in cellular processes.
  • Pharmaceutical Development: The compound serves as a model for developing new drugs. Its mechanism of action provides insights into designing more effective therapies with fewer side effects.
  • Veterinary Medicine: Methotrexate is also applied in treating certain cancers and autoimmune diseases in animals, showcasing its versatility beyond human medicine.

Citations