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Catalog Number:
12881
CAS Number:
148893-10-1
O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
Purity:
≥ 99.5% (HPLC)
Synonym(s):
HATU
Hazmat
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Product Information

HATU is useful as a peptide coupling agent and a catalyst for selective acylation.

Synonyms
HATU
CAS Number
148893-10-1
Purity
≥ 99.5% (HPLC)
Molecular Formula
C10H15F6N6OP
Molecular Weight
0
MDL Number
MFCD00274639
PubChem ID
6409673
Melting Point
183 - 191 °C (dec.)
Appearance
White crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
HATU
CAS Number
148893-10-1
Purity
≥ 99.5% (HPLC)
Molecular Formula
C10H15F6N6OP
Molecular Weight
0
MDL Number
MFCD00274639
PubChem ID
6409673
Melting Point
183 - 191 °C (dec.)
Appearance
White crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

O-(7-Azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a highly effective coupling agent in bioconjugation reactions, allowing researchers to attach biomolecules like proteins and antibodies to surfaces or other molecules, enhancing the functionality of diagnostic and therapeutic agents.
  • Peptide Synthesis: It is commonly used in solid-phase peptide synthesis, providing a reliable method for creating complex peptides with high purity and yield, which is crucial in drug development and research.
  • Fluorescent Labeling: The chemical is employed in the labeling of biomolecules with fluorescent tags, facilitating the study of cellular processes and interactions in live cells, which is essential for biomedical research.
  • Pharmaceutical Development: This compound plays a significant role in the synthesis of pharmaceutical intermediates, streamlining the production of active pharmaceutical ingredients (APIs) and improving the efficiency of drug formulation processes.
  • Material Science: It is utilized in the development of advanced materials, including polymers and coatings, which benefit from enhanced chemical stability and performance, making it valuable in industries like electronics and automotive.

Citations