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Catalog Number:
02484
CAS Number:
163619-04-3
Nα-Fmoc-Nin-Boc-D-tryptophan
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-Trp(Boc)-OH
Documents
$35.30 /1G
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Product Information

Na-Fmoc-Nin-Boc-D-tryptophan is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique combination of protective groups, making it an ideal choice for researchers focused on solid-phase peptide synthesis. Its structure allows for the selective protection of the indole side chain, facilitating the synthesis of complex peptides with enhanced stability and bioactivity. The Fmoc (9-fluorenylmethoxycarbonyl) and Boc (tert-butyloxycarbonyl) groups provide robust protection during the synthesis process, ensuring high yields and purity of the final products.

In practical applications, Na-Fmoc-Nin-Boc-D-tryptophan is particularly valuable in the pharmaceutical industry for developing peptide-based therapeutics, including those targeting neurological disorders and cancer. Its ability to enhance the solubility and stability of peptides makes it a preferred choice among researchers looking to optimize drug formulations. With its unique properties and practical applications, this compound stands out as a crucial tool for advancing peptide chemistry and drug discovery.

Synonyms
Fmoc-D-Trp(Boc)-OH
CAS Number
163619-04-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C31H30N2O6
Molecular Weight
526.6
MDL Number
MFCD00153367
Appearance
White powder
Optical Rotation
[a]D20 = 20 ± 4 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Trp(Boc)-OH
CAS Number
163619-04-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C31H30N2O6
Molecular Weight
526.6
MDL Number
MFCD00153367
Appearance
White powder
Optical Rotation
[a]D20 = 20 ± 4 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nin-Boc-D-tryptophan is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptide chains with high purity and yield.
  • Drug Development: It is used in the development of pharmaceutical compounds, especially those targeting neurological disorders, by facilitating the incorporation of tryptophan derivatives into drug candidates.
  • Bioconjugation: The chemical is valuable in bioconjugation processes, where it helps attach biomolecules to other entities, enhancing the specificity and effectiveness of therapeutic agents.
  • Protein Engineering: Researchers utilize it for modifying proteins, improving their stability and functionality, which is crucial in the production of therapeutic proteins and enzymes.
  • Research in Neuroscience: Its application in neuroscience research is significant, as it aids in studying the role of tryptophan in serotonin production, impacting mood and behavior studies.

Citations