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Catalog Number:
35331
CAS Number:
181817-14-1
Fmoc-O-acetyl-L-threonine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Thr(Ac)-OH
Documents
$66.80 /250MG
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Product Information

Fmoc-O-acetyl-L-threonine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis. Its acetyl group enhances solubility and stability, making it an ideal choice for researchers aiming to optimize peptide sequences for therapeutic applications.

In the pharmaceutical industry, Fmoc-O-acetyl-L-threonine plays a crucial role in the development of peptide-based drugs, particularly those targeting specific biological pathways. Its unique structure allows for the introduction of threonine residues into peptides, which can significantly influence their biological activity and stability. Researchers appreciate its ease of use and compatibility with various coupling reagents, making it a preferred choice for synthesizing complex peptides. This compound not only streamlines the synthesis process but also enhances the overall yield and purity of the final product, ensuring high-quality outcomes in research and development.

Synonyms
Fmoc-L-Thr(Ac)-OH
CAS Number
181817-14-1
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO6
Molecular Weight
383.39
MDL Number
MFCD01861336
PubChem ID
73322531
Melting Point
183 - 185 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 15 ± 2 º (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-L-Thr(Ac)-OH
CAS Number
181817-14-1
Purity
≥ 98% (HPLC)
Molecular Formula
C21H21NO6
Molecular Weight
383.39
MDL Number
MFCD01861336
PubChem ID
73322531
Melting Point
183 - 185 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 15 ± 2 º (C=1 in MeOH)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-acetyl-L-threonine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the efficient assembly of complex peptide structures.
  • Drug Development: It plays a significant role in the pharmaceutical industry, where it is used to develop peptide-based drugs, enhancing the efficacy and specificity of therapeutic agents.
  • Bioconjugation: The chemical is employed in bioconjugation processes, facilitating the attachment of peptides to other biomolecules, which is crucial for the development of targeted drug delivery systems.
  • Research in Protein Engineering: Researchers utilize this compound to modify proteins, enabling the study of protein interactions and functions, which is vital for understanding biological processes.
  • Analytical Chemistry: It is used in analytical methods to characterize peptide structures, helping scientists to confirm the identity and purity of synthesized compounds.

Citations