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Catalog Number:
35203
CAS Number:
374791-02-3
Fmoc-D-azetidine-2-carboxylic acid
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-(R-azetidine-2-carboxylic acid
Documents
$61.29 /250MG
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Product Information

Fmoc-D-azetidine-2-carboxylic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amine functionalities during the synthesis of peptides. Its unique azetidine ring structure enhances the conformational rigidity of peptides, making it a valuable tool for researchers aiming to develop novel therapeutic agents with improved bioactivity and stability.

In addition to its role in peptide synthesis, Fmoc-D-azetidine-2-carboxylic acid is also employed in the development of bioactive compounds and drug candidates, particularly in the fields of oncology and neurology. Its ability to facilitate the incorporation of non-standard amino acids into peptides allows for the exploration of new pharmacological properties. Researchers appreciate its ease of use and compatibility with various coupling reagents, making it an ideal choice for both academic and industrial applications.

Synonyms
Fmoc-(R-azetidine-2-carboxylic acid
CAS Number
374791-02-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C19H17NO4
Molecular Weight
323.34
MDL Number
MFCD01320875
PubChem ID
4430868
Appearance
White to off-white powder
Conditions
Store at RT
General Information
Synonyms
Fmoc-(R-azetidine-2-carboxylic acid
CAS Number
374791-02-3
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C19H17NO4
Molecular Weight
323.34
MDL Number
MFCD01320875
PubChem ID
4430868
Appearance
White to off-white powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-azetidine-2-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex, biologically active molecules.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing new drugs, especially those targeting specific receptors, enhancing the efficacy and selectivity of therapeutic agents.
  • Bioconjugation: Researchers use it to facilitate bioconjugation processes, linking biomolecules with drugs or imaging agents, which is crucial in targeted therapy and diagnostics.
  • Material Science: The compound is applied in the development of novel materials, including polymers and nanomaterials, which can be used in various applications such as drug delivery systems.
  • Research in Chemical Biology: It is utilized in studies that explore protein interactions and functions, providing insights into cellular processes and potential therapeutic targets.

Citations