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Catalog Number:
33641
CAS Number:
193086-74-7
Fmoc-α-methyl-D-2-fluorophenylalanine
Synonym(s):
Fmoc-α-Me-D-Phe(2-F)-OH, Fmoc-(R)-2-amino-2-methyl-3-(2-fluorophenyl)propanoicacid
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$58.39 /100MG
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Product Information

Fmoc-a-methyl-D-2-fluorophenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of a fluorine atom and a methyl group, enhances its stability and reactivity, making it an ideal choice for researchers looking to create complex peptide sequences with precision.

In the pharmaceutical industry, Fmoc-a-methyl-D-2-fluorophenylalanine is particularly beneficial for the development of bioactive peptides, which can serve as potential therapeutics for various diseases. Its application extends to the synthesis of peptide-based drugs and research into protein interactions, where the fluorine atom can aid in improving binding affinities. Researchers appreciate its ease of use in solid-phase peptide synthesis, allowing for efficient and streamlined workflows. With its robust properties and versatility, this compound stands out as a crucial tool for advancing peptide chemistry and drug discovery.

Synonyms
Fmoc-α-Me-D-Phe(2-F)-OH, Fmoc-(R)-2-amino-2-methyl-3-(2-fluorophenyl)propanoicacid
CAS Number
193086-74-7
Molecular Formula
C25H22FNO4
Molecular Weight
419.45
MDL Number
MFCD17019320
PubChem ID
75057028
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-α-Me-D-Phe(2-F)-OH, Fmoc-(R)-2-amino-2-methyl-3-(2-fluorophenyl)propanoicacid
CAS Number
193086-74-7
Molecular Formula
C25H22FNO4
Molecular Weight
419.45
MDL Number
MFCD17019320
PubChem ID
75057028
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-a-methyl-D-2-fluorophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the efficiency and yield of the process.
  • Drug Development: It plays a crucial role in the development of novel pharmaceuticals, especially in designing compounds that target specific biological pathways, thanks to its unique structural properties.
  • Bioconjugation: The chemical is employed in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other compounds, which is essential in creating targeted drug delivery systems.
  • Fluorescent Probes: It is used in the creation of fluorescent probes for biological imaging, enabling scientists to visualize cellular processes in real-time, which is invaluable in research and diagnostics.
  • Structure-Activity Relationship Studies: This compound aids in studying the relationship between the chemical structure of compounds and their biological activity, providing insights that can lead to more effective therapeutic agents.

Citations