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Catalog Number:
11191
CAS Number:
252049-05-1
Fmoc-N-Me-L-norvaline
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-N-Me-L-norvaline, Fmoc-L-N-methyl-2-aminovaleric acid
Documents
$120.58 /1G
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Product Information

Fmoc-N-methyl-L-norvaline is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure not only enhances the stability of the peptide chain but also facilitates the introduction of various functional groups, making it an invaluable tool for researchers in the fields of medicinal chemistry and biochemistry.

The compound's N-methyl substitution provides enhanced lipophilicity, which can improve the bioavailability of peptides in pharmaceutical applications. Fmoc-N-methyl-L-norvaline is particularly beneficial in the development of peptide-based therapeutics, where precise control over amino acid sequences is crucial. Its application extends to the synthesis of cyclic peptides and peptidomimetics, which are gaining traction in drug discovery due to their potential to overcome challenges associated with traditional small molecules. Researchers and industry professionals can leverage this compound to streamline their synthesis processes and enhance the efficacy of their peptide-based products.

Synonyms
Fmoc-N-Me-L-norvaline, Fmoc-L-N-methyl-2-aminovaleric acid
CAS Number
252049-05-1
Purity
≥ 98% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.42
MDL Number
MFCD01861326
PubChem ID
78437290
Melting Point
130.7 - 131.1 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -23 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-N-Me-L-norvaline, Fmoc-L-N-methyl-2-aminovaleric acid
CAS Number
252049-05-1
Purity
≥ 98% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.42
MDL Number
MFCD01861326
PubChem ID
78437290
Melting Point
130.7 - 131.1 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -23 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-N-methyl-L-norvaline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create specific sequences for studying protein interactions and functions.
  • Drug Development: Its unique structure aids in the design of novel pharmaceuticals, particularly in developing drugs that target specific biological pathways, enhancing therapeutic efficacy.
  • Biotechnology: Used in the production of modified proteins, it helps in creating proteins with altered properties, which can be crucial for industrial enzymes and therapeutic proteins.
  • Research in Neuroscience: This compound can be utilized in studies related to neurotransmitter systems, providing insights into neurological disorders and potential treatments.
  • Material Science: Fmoc-N-methyl-L-norvaline is also explored in creating advanced materials, such as hydrogels, which have applications in drug delivery and tissue engineering.

Citations