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Catalog Number:
07329
CAS Number:
136552-06-2
Fmoc-L-azetidine-2-carboxylic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-(S-azetidine-2-carboxylic acid
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Product Information

Fmoc-L-azetidine-2-carboxylic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a unique azetidine ring structure, which enhances its potential as a chiral auxiliary in asymmetric synthesis. Its Fmoc (9-fluorenylmethyloxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing stability during the synthesis process. Researchers and industry professionals appreciate its ability to facilitate the formation of complex peptides, making it an essential tool in the development of pharmaceuticals and biologically active compounds.

The compound's distinctive properties enable its application in various fields, including medicinal chemistry and materials science. For instance, it can be employed in the synthesis of peptide-based therapeutics, where its azetidine structure contributes to the desired biological activity. Additionally, Fmoc-L-azetidine-2-carboxylic acid serves as a valuable intermediate in the preparation of novel drug candidates, offering a pathway to innovative treatments. Its ease of use and effectiveness in enhancing peptide synthesis make it a preferred choice for researchers looking to streamline their workflows and achieve high yields.

Synonyms
Fmoc-(S-azetidine-2-carboxylic acid
CAS Number
136552-06-2
Purity
≥ 99% (HPLC)
Molecular Formula
C19H17NO4
Molecular Weight
323.36
MDL Number
MFCD01320843
PubChem ID
4430868
Melting Point
128 - 132 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -74 ± 1 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-(S-azetidine-2-carboxylic acid
CAS Number
136552-06-2
Purity
≥ 99% (HPLC)
Molecular Formula
C19H17NO4
Molecular Weight
323.36
MDL Number
MFCD01320843
PubChem ID
4430868
Melting Point
128 - 132 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = -74 ± 1 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-azetidine-2-carboxylic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It plays a role in medicinal chemistry, where researchers explore its potential as a scaffold for developing new pharmaceuticals, particularly in targeting specific biological pathways.
  • Bioconjugation: The chemical is used in bioconjugation techniques, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Neuroscience: It is being investigated for its potential applications in neuroscience, particularly in the development of compounds that can modulate neurotransmitter systems.
  • Material Science: Its unique structure allows for applications in material science, particularly in the design of new polymers and materials with specific mechanical properties.

Citations