Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
05138
CAS Number:
198561-07-8
Fmoc-L-propargylglycine
Purity:
≥ 99% (Chiral HPLC)
Synonym(s):
Fmoc-L-propargyl-Gly-OH, Fmoc-L-Pra-OH, Fmoc-Pra-OH
Documents
$80.50 /250MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-L-propargylglycine is a versatile amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a unique propargyl group that enhances its reactivity, making it an ideal building block for the development of bioactive peptides and small molecules. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection, facilitating the synthesis of complex peptide structures. Researchers appreciate its application in click chemistry, particularly in the formation of diverse bioconjugates and drug candidates, which can lead to innovative therapeutic solutions.

In addition to its role in peptide synthesis, Fmoc-L-propargylglycine is also valuable in the development of functionalized materials and nanostructures. Its ability to participate in various coupling reactions expands its utility in creating tailored compounds for specific applications in drug delivery and diagnostics. With its unique properties and broad applicability, Fmoc-L-propargylglycine stands out as a crucial tool for researchers and industry professionals aiming to push the boundaries of chemical synthesis and pharmaceutical development.

Synonyms
Fmoc-L-propargyl-Gly-OH, Fmoc-L-Pra-OH, Fmoc-Pra-OH
CAS Number
198561-07-8
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C20H17NO4
Molecular Weight
335.3
MDL Number
MFCD01075095
PubChem ID
4418905
Melting Point
175 - 177 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -18 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-propargyl-Gly-OH, Fmoc-L-Pra-OH, Fmoc-Pra-OH
CAS Number
198561-07-8
Purity
≥ 99% (Chiral HPLC)
Molecular Formula
C20H17NO4
Molecular Weight
335.3
MDL Number
MFCD01075095
PubChem ID
4418905
Melting Point
175 - 177 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -18 ± 1 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-propargylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a building block in the synthesis of peptides, particularly in the creation of modified peptides that can enhance biological activity or stability.
  • Drug Development: It plays a crucial role in the development of novel therapeutics, especially in the design of inhibitors that target specific enzymes or receptors in various diseases.
  • Bioconjugation: The alkyne group in Fmoc-L-propargylglycine allows for click chemistry applications, enabling researchers to attach biomolecules to surfaces or other molecules efficiently.
  • Research in Neuroscience: This compound is used in studies related to neuropeptides, aiding in the understanding of neurological pathways and potential treatments for neurodegenerative diseases.
  • Material Science: It is also explored in the development of smart materials that respond to environmental stimuli, showcasing its versatility beyond traditional applications.

Citations