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Catalog Number:
02691
CAS Number:
135112-27-5
Fmoc-L-α-aminobutyric acid
Purity:
≥ 99.5% (Chiral purity)
Synonym(s):
Fmoc-L-Abu-OH, Fmoc-L-2-aminobutanoic acid
Documents
$18.53 /1G
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Product Information

Fmoc-L-a-aminobutyric acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during the synthesis of peptides. Its unique structure allows for easy cleavage under mild conditions, making it an ideal choice for researchers focused on developing complex peptide sequences. The compound is particularly valuable in the pharmaceutical industry for the design of novel therapeutics, including peptide-based drugs and biologics.

In addition to its role in peptide synthesis, Fmoc-L-a-aminobutyric acid is also employed in various research applications, including studies on protein interactions and enzyme activity. Its stability and compatibility with different coupling reagents enhance its utility in diverse chemical environments. Researchers appreciate its ability to facilitate the synthesis of peptides with high purity and yield, which is crucial for subsequent biological evaluations. With its broad applicability and efficiency, Fmoc-L-a-aminobutyric acid stands out as a key reagent for professionals in the fields of biochemistry and pharmaceutical development.

Synonyms
Fmoc-L-Abu-OH, Fmoc-L-2-aminobutanoic acid
CAS Number
135112-27-5
Purity
≥ 99.5% (Chiral purity)
Molecular Formula
C19H19NO4
Molecular Weight
325.4
MDL Number
MFCD00080268
PubChem ID
4248192
Melting Point
131 - 137 ºC
Appearance
White powder or white crystalline powder
Optical Rotation
[a]D20 = -23 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Abu-OH, Fmoc-L-2-aminobutanoic acid
CAS Number
135112-27-5
Purity
≥ 99.5% (Chiral purity)
Molecular Formula
C19H19NO4
Molecular Weight
325.4
MDL Number
MFCD00080268
PubChem ID
4248192
Melting Point
131 - 137 ºC
Appearance
White powder or white crystalline powder
Optical Rotation
[a]D20 = -23 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-a-aminobutyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Its application in the design of peptide-based drugs helps in creating more effective therapeutic agents, particularly in targeting specific biological pathways.
  • Bioconjugation: The chemical is used in bioconjugation processes to attach biomolecules to surfaces or other molecules, enhancing the functionality of diagnostic tools and drug delivery systems.
  • Research in Neuroscience: It plays a role in the synthesis of neuropeptides, which are crucial for understanding neurological functions and developing treatments for neurological disorders.
  • Custom Peptide Libraries: Researchers utilize it to create diverse peptide libraries for screening potential drug candidates, facilitating the discovery of novel therapeutics.

Citations