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Catalog Number:
36981
CAS Number:
80049-85-0
Suc-Gly-Pro-AMC
Purity:
≥96% (Purity by HPLC)
Documents
$113.70 /5MG
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Product Information

Suc-Gly-Pro-AMC is a highly valuable compound recognized for its role as a substrate in protease assays, particularly in the study of enzyme kinetics and inhibition. This synthetic peptide is characterized by its unique structure, which includes a fluorogenic moiety that allows for sensitive detection of enzymatic activity. Researchers in biochemistry and molecular biology utilize Suc-Gly-Pro-AMC for its ability to provide real-time monitoring of protease activity, making it an essential tool in drug discovery and development, especially in the context of therapeutic interventions targeting proteolytic enzymes.

The compound's specificity and sensitivity make it particularly advantageous for applications in cancer research, where proteases play a crucial role in tumor progression and metastasis. Additionally, Suc-Gly-Pro-AMC can be employed in various biochemical assays to study protein interactions and modifications, offering insights into cellular processes. Its ease of use and reliable performance in diverse experimental setups further enhance its appeal to researchers seeking to advance their understanding of proteolytic mechanisms.

CAS Number
80049-85-0
Purity
≥96% (Purity by HPLC)
Molecular Formula
C21H23N3O7
Molecular Weight
429.43
PubChem ID
3258144
Conditions
Store at ≤ -20°C
General Information
CAS Number
80049-85-0
Purity
≥96% (Purity by HPLC)
Molecular Formula
C21H23N3O7
Molecular Weight
429.43
PubChem ID
3258144
Conditions
Store at ≤ -20°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Suc-Gly-Pro-AMC is widely utilized in research focused on:

  • Protease Activity Measurement: This compound serves as a substrate for various proteases, allowing researchers to measure enzyme activity in biological samples. Its specificity helps in identifying particular protease functions, which is crucial in drug development and disease research.
  • Drug Discovery: In pharmaceutical research, Suc-Gly-Pro-AMC is used to screen for inhibitors of proteases that are implicated in diseases such as cancer and viral infections. This application accelerates the identification of potential therapeutic agents.
  • Biochemical Assays: It is employed in biochemical assays to study protein interactions and modifications. The compound's fluorescent properties enable real-time monitoring, providing valuable insights into cellular processes.
  • Diagnostic Applications: Suc-Gly-Pro-AMC can be used in diagnostic tests for diseases that involve protease activity, offering a reliable method for assessing disease progression and treatment efficacy.
  • Research in Neuroscience: This compound is also utilized in neuroscience research to investigate the role of proteases in neurodegenerative diseases, helping to uncover mechanisms that could lead to new therapeutic strategies.

Citations