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Catalog Number:
00127
CAS Number:
3483-12-3, 27565-41-9
1,4-Dithio-DL-threitol
Purity:
≥ 99% (Assay by titration)
Synonym(s):
DTT, Cleland's reagent, threo-1,4-Dimercapto-2,3-butanediol
Documents
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Product Information

1,4-Dithio-DL-threitol is a versatile thiol compound known for its unique properties and applications in various fields. This compound, with its two sulfanyl groups, exhibits strong reducing capabilities, making it an excellent choice for applications in biochemistry and molecular biology. Researchers often utilize 1,4-Dithio-DL-threitol as a reducing agent in protein chemistry, particularly for the stabilization of thiol groups in proteins and enzymes. Its ability to maintain the reduced state of cysteine residues is crucial in preserving protein structure and function during experimental procedures.

In addition to its role in protein stabilization, 1,4-Dithio-DL-threitol serves as a valuable tool in the synthesis of other chemical compounds and in the formulation of pharmaceuticals. Its unique structure allows for easy incorporation into various chemical reactions, enhancing the efficiency of synthetic pathways. This compound is particularly beneficial in the development of antioxidant formulations, where it can help mitigate oxidative stress in biological systems. With its broad range of applications, 1,4-Dithio-DL-threitol stands out as a key reagent for researchers and industry professionals seeking reliable solutions in their work.

Synonyms
DTT, Cleland's reagent, threo-1,4-Dimercapto-2,3-butanediol
CAS Number
3483-12-3, 27565-41-9
Purity
≥ 99% (Assay by titration)
Molecular Formula
C4H10O2S2
Molecular Weight
154.24
MDL Number
MFCD00004877
PubChem ID
19001
Melting Point
40 - 44 °C
Appearance
White crystals or free flowing powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
DTT, Cleland's reagent, threo-1,4-Dimercapto-2,3-butanediol
CAS Number
3483-12-3, 27565-41-9
Purity
≥ 99% (Assay by titration)
Molecular Formula
C4H10O2S2
Molecular Weight
154.24
MDL Number
MFCD00004877
PubChem ID
19001
Melting Point
40 - 44 °C
Appearance
White crystals or free flowing powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1,4-Dithio-DL-threitol is widely utilized in research focused on:

  • Antioxidant Applications: This compound serves as a potent antioxidant, helping to protect cells from oxidative stress in biological research, which is crucial for studies on aging and disease prevention.
  • Biochemical Studies: It is used in various biochemical assays to stabilize proteins and enzymes, enhancing their activity and reliability in experimental settings.
  • Pharmaceutical Development: In drug formulation, it acts as a reducing agent, improving the stability and efficacy of certain pharmaceutical compounds, particularly in the development of new therapies.
  • Cosmetic Industry: The compound is incorporated into skincare products for its skin-protective properties, helping to combat free radicals and promote healthier skin.
  • Research on Metal Chelation: It is utilized in studies involving metal ions, aiding in the chelation process, which is important in environmental science and toxicology research.

Citations