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Catalog Number:
33326
4-Methoxytrityl chloride resin (1.0-1.6 mmol/g, 100-200 mesh)
Documents
$30.00 /1G
Pack Size Availability Price
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Product Information

4-Methoxytrityl chloride resin is a highly versatile reagent widely utilized in organic synthesis and peptide chemistry. This resin, characterized by its functional group density of 1.0 - 1.6 mmol/g and a mesh size of 100 - 200, serves as an excellent support for solid-phase synthesis. Its unique methoxytrityl group provides enhanced protection for hydroxyl functionalities, making it an ideal choice for the synthesis of complex organic molecules and oligonucleotides. Researchers appreciate its stability and efficiency, which facilitate streamlined workflows in laboratory settings.

In practical applications, 4-Methoxytrityl chloride resin is particularly valuable in the field of medicinal chemistry, where it aids in the development of pharmaceuticals by enabling the selective protection of reactive sites. Its use in automated synthesizers allows for high-throughput screening and rapid compound generation, significantly accelerating research timelines. Additionally, the resin's compatibility with various coupling reagents enhances its utility in diverse chemical environments, making it a preferred choice for professionals seeking reliable and effective solutions in their synthetic endeavors.

MDL Number
MFCD00281965
Appearance
Yellow beads
Substitution
1.0 - 1.6 mmol/g
Mesh Size
100 - 200 mesh
Conditions
Store at 2 - 8 °C
%DVB
2% DVB
General Information
MDL Number
MFCD00281965
Appearance
Yellow beads
Substitution
1.0 - 1.6 mmol/g
Mesh Size
100 - 200 mesh
Conditions
Store at 2 - 8 °C
%DVB
2% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Methoxytrityl chloride resin is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This resin is essential for solid-phase synthesis of oligonucleotides, providing a reliable support for attaching nucleotides, which is crucial in genetic research and therapeutic applications.
  • Peptide Synthesis: It serves as a protective group in peptide synthesis, allowing chemists to selectively modify amino acids while preventing unwanted reactions, thus enhancing the purity and yield of the final product.
  • Drug Development: In pharmaceutical research, this resin aids in the development of new drugs by facilitating the synthesis of complex molecules, streamlining the process of creating potential therapeutic agents.
  • Bioconjugation: The resin is utilized in bioconjugation techniques, helping to attach biomolecules to surfaces or other molecules, which is important in creating targeted drug delivery systems.
  • Analytical Chemistry: It is used in the preparation of samples for analytical techniques, improving the efficiency and accuracy of chemical analysis in various research settings.

Citations