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Catalog Number:
33322
4-Methoxytrityl chloride resin (0.4 - 1.0 mmol/g, 200 - 400 mesh)
Documents
$29.34 /1G
Pack Size Availability Price
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Product Information

4-Methoxytrityl chloride resin is a versatile and highly effective reagent widely utilized in the field of organic synthesis and peptide chemistry. This resin, characterized by its functional group density of 0.4 - 1.0 mmol/g and mesh size of 200 - 400, serves as an excellent support for solid-phase synthesis. Its unique methoxytrityl group provides a protective function for hydroxyl groups, making it particularly valuable in the synthesis of oligonucleotides and complex organic molecules. Researchers appreciate its ability to facilitate the selective deprotection of functional groups, allowing for precise control over reaction pathways and product formation.

In addition to its application in oligonucleotide synthesis, 4-Methoxytrityl chloride resin is also employed in the development of various pharmaceuticals and biologically active compounds. Its high loading capacity and compatibility with a range of solvents enhance its utility in diverse synthetic protocols. The resin's stability under various reaction conditions ensures reliable performance, making it a preferred choice for chemists seeking efficiency and reproducibility in their work. With its proven track record in both academic and industrial settings, this resin is an essential tool for professionals aiming to streamline their synthesis processes.

MDL Number
MFCD00281965
Appearance
Yellow beads
Substitution
0.4 - 1.0 mmol/g
Mesh Size
200 - 400 mesh
Conditions
Store at 2 - 8 °C
%DVB
1% DVB
General Information
MDL Number
MFCD00281965
Appearance
Yellow beads
Substitution
0.4 - 1.0 mmol/g
Mesh Size
200 - 400 mesh
Conditions
Store at 2 - 8 °C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Methoxytrityl chloride resin is widely utilized in research focused on

  • Solid-Phase Synthesis: This resin is essential in the solid-phase synthesis of peptides and nucleotides, allowing for efficient and controlled assembly of complex molecules.
  • Protecting Group Applications: It serves as a protecting group for hydroxyl and amine functionalities during organic synthesis, enhancing the selectivity and yield of reactions.
  • Drug Development: In pharmaceutical research, it aids in the synthesis of drug candidates by facilitating the formation of specific molecular structures, streamlining the drug discovery process.
  • Bioconjugation: The resin is used in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules, crucial for developing diagnostics and therapeutics.
  • Custom Polymer Development: Researchers leverage this resin for creating custom polymers with tailored properties, which can be applied in various fields, including materials science and nanotechnology.

Citations