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Catalog Number:
30323
CAS Number:
1425938-63-1
Fmoc-Thr(tBu)-Ser[Psi(Me,Me)Pro]-OH
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-Thr(tBu)-Ser[Ψ(Me,Me)Pro]-OH, (4S)-3-[N-(9-Fluorenylmethyloxycarbonyl-O-tert-butyl-L-threoninyl]-2,2-dimethyl-oxazolidine-4-carboxylicacid
Antibiotic
Documents
$77.82 /1G
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Product Information

Fmoc-Thr(tBu)-Ser[Psi(Me,Me)Pro]-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely recognized for its effectiveness in solid-phase peptide synthesis. The presence of the t-butyl (tBu) group enhances the stability and solubility of the compound, making it particularly valuable for researchers working in the fields of medicinal chemistry and biochemistry. Its unique structure, including the Psi(Me,Me)Pro configuration, allows for the incorporation of this amino acid into peptides with enhanced biological activity, providing opportunities for the development of novel therapeutics.

This compound is ideal for applications in the synthesis of complex peptides and proteins, where precise control over amino acid sequences is essential. Researchers can leverage Fmoc-Thr(tBu)-Ser[Psi(Me,Me)Pro]-OH to create peptides with improved pharmacokinetic properties, potentially leading to more effective drug candidates. Its compatibility with various coupling reagents and solid-phase techniques further underscores its utility in peptide chemistry, making it a preferred choice for professionals seeking to innovate in peptide-based drug design.

Synonyms
Fmoc-Thr(tBu)-Ser[Ψ(Me,Me)Pro]-OH, (4S)-3-[N-(9-Fluorenylmethyloxycarbonyl-O-tert-butyl-L-threoninyl]-2,2-dimethyl-oxazolidine-4-carboxylicacid
CAS Number
1425938-63-1
Purity
≥ 99% (HPLC)
Molecular Formula
C29H36N2O7 
Molecular Weight
524.61
MDL Number
MFCD02682878
PubChem ID
77891374
Appearance
White powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-Thr(tBu)-Ser[Ψ(Me,Me)Pro]-OH, (4S)-3-[N-(9-Fluorenylmethyloxycarbonyl-O-tert-butyl-L-threoninyl]-2,2-dimethyl-oxazolidine-4-carboxylicacid
CAS Number
1425938-63-1
Purity
≥ 99% (HPLC)
Molecular Formula
C29H36N2O7 
Molecular Weight
524.61
MDL Number
MFCD02682878
PubChem ID
77891374
Appearance
White powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Fmoc-Thr(tBu)-Ser[Psi(Me,Me)Pro] is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity and yield.
  • Drug Development: Its unique structure makes it valuable in the pharmaceutical industry for developing peptide-based drugs, especially those targeting specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: This chemical is used in bioconjugation processes to attach peptides to various biomolecules, facilitating the development of targeted drug delivery systems and improving the specificity of therapeutic agents.
  • Research in Protein Engineering: Researchers utilize this compound to modify proteins, enabling the study of protein interactions and functions, which is crucial for understanding diseases and developing new treatments.
  • Analytical Chemistry: It plays a role in analytical methods for characterizing peptides and proteins, providing insights into their structure and function, which is essential for quality control in biopharmaceuticals.

Citations