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Catalog Number:
30317
CAS Number:
1196703-48-6
Fmoc-Phe-Thr[Psi(Me,Me)Pro]-OH
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-Phe-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[N-(9-Fluorenylmethyloxycarbonyl)-L-phenylalaninyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
Antibiotic
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$75.00 /1G
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Product Information

Fmoc-Phe-Thr[Psi(Me,Me)Pro]-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its ability to enhance the stability and bioactivity of peptides, making it an essential tool for researchers in the fields of medicinal chemistry and biochemistry. Its unique structure, featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group, allows for selective deprotection during synthesis, facilitating the construction of complex peptide sequences.

In practical applications, Fmoc-Phe-Thr[Psi(Me,Me)Pro]-OH is often utilized in the development of peptide-based therapeutics, where its incorporation can improve pharmacokinetic properties and target specificity. Researchers have found that this compound can be effectively used in solid-phase peptide synthesis, enabling the efficient assembly of peptides with enhanced stability and activity. Its unique properties make it a preferred choice for professionals seeking to optimize peptide design and functionality in various applications, including drug discovery and development.

Synonyms
Fmoc-Phe-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[N-(9-Fluorenylmethyloxycarbonyl)-L-phenylalaninyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
CAS Number
1196703-48-6
Purity
≥ 99% (HPLC)
Molecular Formula
C31H32N2O6
Molecular Weight
528.6
MDL Number
MFCD18427357
PubChem ID
129011252
Appearance
White powder
Optical Rotation
[a]D25 = -26 ± 2.5 ° (C=1 in MeOH)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-Phe-Thr[Ψ(Me,Me)Pro]-OH, (4S,5R)-3-[N-(9-Fluorenylmethyloxycarbonyl)-L-phenylalaninyl]-2,2,5-trimethyloxazolidine-4-carboxylicacid
CAS Number
1196703-48-6
Purity
≥ 99% (HPLC)
Molecular Formula
C31H32N2O6
Molecular Weight
528.6
MDL Number
MFCD18427357
PubChem ID
129011252
Appearance
White powder
Optical Rotation
[a]D25 = -26 ± 2.5 ° (C=1 in MeOH)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Fmoc-Phe-Thr[Psi(Me,Me)Pro]-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with specific functionalities. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group facilitates easy deprotection during synthesis.
  • Drug Development: In pharmaceutical research, it is used to develop peptide-based drugs, particularly in targeting specific biological pathways. This compound's unique structure can enhance the bioactivity of therapeutic peptides.
  • Bioconjugation: It plays a crucial role in bioconjugation processes, where it can be linked to other biomolecules, improving the efficacy of drug delivery systems or diagnostic agents.
  • Protein Engineering: Researchers utilize this compound to modify proteins, enhancing their stability and activity. This is particularly beneficial in the development of enzymes and antibodies for industrial applications.
  • Academic Research: It is frequently employed in academic laboratories for studies related to protein interactions and structure-function relationships, providing insights that can lead to new discoveries in biochemistry.

Citations