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Catalog Number:
30306
CAS Number:
909115-33-9
Fmoc-Glu(OtBu)-Ser[Psi(Me,Me)Pro]-OH
Purity:
≥ 99% (Assay by titration)
Synonym(s):
Fmoc-Glu(OtBu)-Ser[Ψ(Me,Me)Pro]-OH, (S)-3-[Na-(9-Fluorenylmethyloxycarbonyl)-L-glutamyl-tert-butylester]-2,2-dimethyloxazolidine-4-carboxylic acid
Antibiotic
Documents
$77.82 /1G
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Product Information

Fmoc-Glu(OtBu)-Ser[Psi(Me,Me)Pro]-OH is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued in the field of medicinal chemistry and biochemistry for its ability to facilitate the formation of complex peptide structures. Its unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection under mild conditions, making it an ideal choice for researchers looking to synthesize peptides with high precision and efficiency.

In addition to its utility in peptide synthesis, Fmoc-Glu(OtBu)-Ser[Psi(Me,Me)Pro]-OH is also recognized for its potential applications in the development of therapeutic agents, particularly in the design of peptide-based drugs that target specific biological pathways. Its structural features enhance solubility and stability, which are critical factors in drug formulation. Researchers and industry professionals can leverage this compound to create innovative solutions in drug discovery and development, making it an essential addition to any laboratory focused on peptide chemistry.

Synonyms
Fmoc-Glu(OtBu)-Ser[Ψ(Me,Me)Pro]-OH, (S)-3-[Na-(9-Fluorenylmethyloxycarbonyl)-L-glutamyl-tert-butylester]-2,2-dimethyloxazolidine-4-carboxylic acid
CAS Number
909115-33-9
Purity
≥ 99% (Assay by titration)
Molecular Formula
C30H36N2O8
Molecular Weight
552.62
MDL Number
MFCD18427719
PubChem ID
129011247
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -37.5 ± 3.5 º (C=1 in CH2Cl2)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-Glu(OtBu)-Ser[Ψ(Me,Me)Pro]-OH, (S)-3-[Na-(9-Fluorenylmethyloxycarbonyl)-L-glutamyl-tert-butylester]-2,2-dimethyloxazolidine-4-carboxylic acid
CAS Number
909115-33-9
Purity
≥ 99% (Assay by titration)
Molecular Formula
C30H36N2O8
Molecular Weight
552.62
MDL Number
MFCD18427719
PubChem ID
129011247
Appearance
White to off-white powder
Optical Rotation
[a]D25 = -37.5 ± 3.5 º (C=1 in CH2Cl2)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Fmoc-Glu(OtBu)-Ser[Psi(Me,Me)Pro]-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptide sequences efficiently.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing peptide-based drugs, which can target specific biological pathways, offering potential treatments for various diseases.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps link peptides to other biomolecules, enhancing the stability and efficacy of therapeutic agents.
  • Research in Protein Engineering: Researchers utilize this compound to modify proteins, enabling the study of protein interactions and functions, which is crucial for understanding biological processes.
  • Diagnostic Applications: It can be incorporated into diagnostic assays, aiding in the development of sensitive detection methods for biomarkers in clinical settings.

Citations